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211. [BIPS Project] Utilization of drugs containing testosterone in Germany   Drugs containing testosterone are indicated in the treatment of testosterone deficiency caused by a malfunction of the testes, for the treatment of a delayed onset of puberty in boys as well as to…  
212. [BIPS Project] Use of routine data for pharmacovigilance in Germany: Method development and initial applications   Adverse drug events are one of the most frequent causes of death. There are market withdrawals for pharmaceutical products from time to time, because severe side effects were not recognized before…  
213. [BIPS Project] Use of population databases with double sampling for choice-based sample surveys and time-to-event data (Project in the Priority Programme on Survey Methodology)   Two-phase or double sampling methods were developed for studies with missing or imprecise covariate information. These methods are typically applied, if information on the event and crude information…  
214. [BIPS Project] Use of parenteral Iron-(III)-products in Germany   Parenteral iron (III) preparations are used since the 1950s for the treatment of iron deficiency, if oral iron preparations are not effective or cannot be used. Due to safety concerns due to…  
215. [BIPS Project] Use of opioid-containing drugs in Germany   Opioids are among the most effective drugs to treat moderate to severe pain. Considering the WHO analgesic ‘ladder’, their use in tumor-related pain, acute pain, and palliative care is…  
216. [BIPS Project] Use of combined oral contraceptives and risk of venous thromboembolism   Combined hormonal contraceptives (CHC) are the most widely used method of birth control in Germany. In 2018, an estimated 210 million daily doses covered by statutory health insurance providers were…  
217. [BIPS Project] Use of carbimazole, thiamazole and propylthiouracil during pregnancy in Germany   The treatment of Graves' disease in girls and women of childbearing age is particularly challenging due to the potential occurrence of pregnancy. Failure to treat the hyperthyroidism associated with…  
218. [BIPS Project] Two-phase methodology for the combined analysis of secondary data sources   Administrative data of statutory health insurances are a valuable data source for pharmacoepidemiological studies and health services research. The validity of studies based on these data might be…  
219. [BIPS Project] The use of MS-medications in girls and women of childbearing age and during pregnancy in Germany   Multiple sclerosis (MS) is the most common central nervous autoimmune disease in Germany with a typical onset in early adulthood between the ages of 20 and 40. Women are about three times more likely…  
220. [BIPS Project] The intelligent digital guideline editor (IDEAL): applying causal inference to evidence generation using emulated clinical trials   The focus of the project IDEAL is the development of a methodology to use causal inference and adaptive statistical procedures to simplify the planning of efficient clinical studies and to be able to…  
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