Search - Leibniz Institute for Prevention Research and Epidemiology

261. [BIPS Project] PAS-study for Entresto® (sacubitril/valsartan)

URL: /en/research/projects/detail-view.html?projID=802&cHash=8dbc9f677411b8e8f05616aac3f934c1
Date: 01-01-19

Angiotensin II antagonists (e.g. valsartan, lorsartan) are substances that lower blood pressure and cause vasodilation by modulating the renin-angiotensin system. Besides hypertension, some…

262. [BIPS Project] PAS-study for eliglustat

URL: /en/research/projects/detail-view.html?projID=918&cHash=d876d3358dfbd42e2702cd0b2b6dc02e
Date: 30-06-21

Drug utilisation study of eliglustat for the treatment of Gaucher disease type 1 in Europe using electronic healthcare records Gaucher disease (GD) is a rare genetic disorder from the group of…

263. [BIPS Project] PAS-study for Brodalumab

URL: /en/research/projects/detail-view.html?projID=850&cHash=ca3027fc09de94936039549eef3d157e
Date: 01-10-19

"The Brodalumab assessment of hazards: A multinational safety study in electronic healthcare databases" Brodalumab (Kyntheum®) is a new monoclonal antibody for the treatment of moderate to severe…

264. [BIPS Project] PAS-study for alemtuzumab

URL: /en/research/projects/detail-view.html?projID=943&cHash=1349154bbd11f321c29994b2f766c31a
Date: 21-06-21

Alemtuzumab (LEMTRADA®), a highly efficacious disease modifying therapy (HE-DMT), is a monoclonal antibody indicated for the treatment of relapsing remitting multiple sclerosis (RRMS) in patients…

265. [BIPS Project] NFDI4Health - Task Force COVID-19: Better understanding the COVID-19 outbreak and its consequences through integrated and harmonised research efforts

URL: /en/research/projects/detail-view.html?projID=879&cHash=95a3309d572f6d84268304d97e9e7947
Date: 01-07-20

COVID-19 poses a major challenge to individuals and societies around the world. Lockdown efforts dramatically change social lives, economic prospects and health services. This creates a huge demand…

266. [BIPS Project] National research data infrastructure for personal health data

URL: /en/research/projects/detail-view.html?projID=864&cHash=f45183b650869512d8f2c6f1a9239211
Date: 01-10-20

Germany has accumulated a wealth of health-related personal data from well-designed cohort studies and health surveillance systems (healthy individuals) as well as clinical trials (patients) that are…

267. [BIPS Project] Monitoring of physical activity and promotion of physical activity - development of indicators for the prevention indicator system of the federal states

URL: /en/research/projects/detail-view.html?projID=1043&cHash=d5b15903aa14fb17645e92efe10f252a
Date: 01-03-23

The Prevention Act considers physical activity promotion as an integral part of the German National Health Goals and thus part of the federal framework recommendations and state framework agreements.…

268. [BIPS Project] Modeling of gene-gene- and gene-environment-interactions in genetic epidemiology using directed graphs

URL: /en/research/projects/detail-view.html?projID=179&cHash=116ee52b506b4d3685dde4364e747213
Date: 01-08-04

This project uses directed graphs for modelling gene-gene- and gene-environment-interactions in genetic epidemiology. At present the work is focused on graphical models. Background: In genetic…

269. [BIPS Project] Microbiome influence on energy balance and brain development-function put into action to tackle diet-related diseases and behavior (MyNewGut)

URL: /en/research/projects/detail-view.html?projID=541&cHash=c474ca122b33b13021830f4b78d0d87d
Date: 01-12-13

Emerging evidence indicates that the gut microbiome contributes to our ability to extract energy from the diet and influences development and function of the immune, endocrine and nervous systems,…

270. [BIPS Project] Mental health and gender: Development and evaluation of a digital intervention for health promotion among informal caregivers

URL: /en/research/projects/detail-view.html?projID=875&cHash=fd0523abd556707904db27f684f126e0
Date: 01-04-21

Women more frequently provide unpaid care than men, while at the same time being exposed to larger caregiving-related mental-health effects than male caregivers. Existing prevention and health…