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Biomarkers4Pediatrics - International Multicohort Pediatric Biomarker Collaboration

Biomarkers4Pediatrics is a recently established initiative that brings together international population-based studies in children and adolescent populations with biomarkers and anthropometric and physiological measurements collected. By pooling data from various pediatric populations across the world, we aim to address important research questions advancing primary prevention and clinical decision making in global pediatric health.

One of our initial objectives is to develop a global definition of pediatric metabolic syndrome.


To contact the Biomarkers4Pediatrics team, please email biomarkers4peds(at) We are open for new studies.

About Biomarkers4Pediatrics

Biomarkers4Pediatrics aim to establish a large, globally collaborating network on pediatric biomarkers. The initiative led by the Leibniz Institute for Prevention Research and Epidemiology - BIPS has been supported by leading researchers in pediatric health. Several renown international child and adolescent studies have already joined (see “Studies that contribute their data” below). Taking advantage of increased statistical power and variations across age groups, geographical regions and socio-cultural backgrounds, we aim at conducting pooled data analyses on a global scale and provide age-, sex- and ethnic-specific reference curves for metabolic biomarkers to facilitate the diagnosis of metabolic syndrome in early life.


  1. Harmonize and pool data from population-based studies in children and adolescent populations (aged 0-18 years) with relevant biomarkers as well as  anthropometric and physiological measurements.
  2. Perform joint analyses on research questions in pediatric health using pooled harmonized datasets.

The Team

Prof Dr Iris Pigeot, Scientific Director & Head Department of Biometry and Data Management
Prof Dr Wolfgang Ahrens, Head Department of Epidemiological Methods and Etiological Research

Prof Dr Sørge Kelm, Department of Biology and Chemistry, University Bremen, Germany.

Prof Ruan Kruger,  Faculty of Health Sciences, North-West University, South Africa.

Prof Luis A. Moreno Aznar, University of Zaragoza, Spain.

Prof Roya Kelishadi, Isfahan University of Medical Sciences, Iran.

Dr. Robinson Ramírez-Vélez, Universidad Pública de Navarra, Columbia.

Studies & Data

 Number of studies/cohortsNumber of countriesSample size
Pooled and harmonized61293.000

  ZUTAS - Zanzibar Nutrition and Health Survey (2013 & 2021) [Tanzania]
  NHANES - United States National Health and Nutrition Examination Survey [United States]
  CASPIAN - Childhood and Adolescence Surveillance and Prevention of Adult Non-Communicable Disease [Iran]
  CHNS - China Health and Nutrition Survey [China]
  KNHANES - Korea National Health and Nutrition Examination Survey [South Korea]
  ALSPAC - Avon Longitudinal Study of Parents and Children [United Kingdom]
  DEGS - German Health Interview and Examination Survey for Adults [Germany]
  IDEFICS/I.Family - Identification and prevention of Dietary- and lifestyle-induced health Effects in Children and Infants cohort study [Belgium, Cyprus, Estonia, Germany, Hungary, Italy, Poland, Spain and Sweden]
  KIGGS - German Health Interview and Examination Survey for Children and Adolescents (Baseline, Wave 2) [Germany]

Key Documents

Data Use Agreement (incl. authorship policy)
Data Collection Sheet