Dr. Tania Schink

• Drug and vaccine safety, esp. during pregnancy
• Use of electronic health record data for pharmacoepidemiologogical research
• Causal Inference

• International Society for Pharmacoepidemiology (ISPE)
• German Society for Epidemiology (Deutsche Gesellschaft für Epidemiologie / DGEpi)
• German Society for Medical Informatics, Biometrics and Epidemiology (Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie / GMDS)
• International Biometric Society (Deutsche Region der Internationalen Biometrischen Gesellschaft / IBS-DR)

• Prescription behavior of HIV therapeutics in women of childbearing age and during pregnancy in Germany
• Studying drug safety during pregnancy based on routine data in Germany
• Use of carbimazole, thiamazole and propylthiouracil during pregnancy in Germany
• Use of combined oral contraceptives and risk of venous thromboembolism

Selected BIPS-Publications

• Articles with peer review

• Wittström F, Cesta CE, Bateman BT, Bendix M, Bliddal M, Chan AYL, Cho Y, Choi E-Y, Cohen JM, Donald S, Gissler M, Havard A, Hernandez-Diaz S, Huybrechts KF, Kollhorst B, Leinonen MK, Li BMH, Man KKC, Ng VWS, Parkin L, Pazzagli L, Rasmussen L, Rotem RS, Schink T, Shin J-Y, Tran DT, Wong ICK, Zoega H, Reutfors J. Lithium use during pregnancy in 14 countries. JAMA Network Open. 2024;7(12):e2451117.
  https://doi.org/10.1001/jamanetworkopen.2024.51117
  https://repository.publisso.de/resource/frl%3A6526128
• Haug U, Kollhorst B, Schink T, Thöne K, Dathe K, Schaefer C, Onken M. Investigating drug safety in pregnancy based on the German Pharmacoepidemiological Research Database (GePaRD): A proof-of-concept analysis on the association between valproate and spina bifida. Pharmacoepidemiology and Drug Safety. 2023;32(2):148-157.
  https://doi.org/10.1002/pds.5573
• Platzbecker K, Müller-Fielitz H, Foraita R, Koepp MJ, Voss A, Pflock R, Linder R, Pigeot I, Schink T, Schwaninger M. In atrial fibrillation epilepsy risk differs between oral anticoagulants: Active comparator, nested case control study. Europace. 2023;25(5):euad087.
  https://doi.org/10.1093/europace/euad087
• Asendorf M, Reinold J, Schink T, Kollhorst B, Haug U. Abbildbarkeit des sozioökonomischen Status in der pharmakoepidemiologischen Forschungsdatenbank GePaRD: Beschreibung und Anwendung am Beispiel des Zusammenhangs mit Adipositas. GMS Medizinische Informatik, Biometrie und Epidemiologie. 2022;18(1):Doc02.
  https://doi.org/10.3205/mibe000235
• Platzbecker K, Voss A, Reinold J, Elbrecht A, Biewener W, Prieto-Alhambra D, Jödicke A, Schink T. Validation of algorithms to identify acute myocardial infarction, stroke, and cardiovascular death in German health insurance data. Clinical Epidemiology. 2022;14:1351-1361.
  https://doi.org/10.2147/CLEP.S380314
• Thurin N, Pajouheshina R, Roberto G, Dodd C, Hyeraci G, Bartolini C, Paoletti O, Nordeng H, Wallach-Kidemoes H, Ehrenstein V, Dudukina E, MacDonald T, De Paoli G, Loane M, Damase Michel C, Beau A-B, Droz-Perroteau C, Lassalle R, Bergmann J, Swart K, Schink T, Cavero-Carbonell C, Barrachina-Bonet L, Gomez-Lumbreras A, Giner-Soriano M, Aragon M, Neville A, Puccini A, Pierini A, Ientile V, Trifirò G, Rissmann A, Leinonen M, Martikainen V, Jordan S, Thayer D, Scanlon I, Georgiou M, Cunnington M, Swertz M, Sturkenboom MCJM, Gini R. From inception to ConcePTION: Genesis of a network to support better monitoring and communication of medication safety during pregnancy and breastfeeding. Clinical Pharmacology and Therapeutics. 2022;111(1):321-331.
  https://doi.org/10.1002/cpt.2476
• Schäfer W, Wentzell N, Schink T, Haug U. Characterization of pregnancies exposed to St. John's wort and their outcomes: A claims data analysis. Reproductive Toxicology. 2021;102:90-97.
  https://doi.org/10.1016/j.reprotox.2021.04.005
  https://repository.publisso.de/resource/frl%3A6428346
• Gini R, Sturkenboom MCJM, Sultana J, Cave A, Landi A, Pacurariu A, Roberto G, Schink T, Candore G, Slattery J, Trifirò G, on behalf of the Working Group 3 of ENCePP. Different strategies to execute multi-database studies for medicines surveillance in real-world setting: A reflection on the European model. Clinical Pharmacology and Therapeutics. 2020;108(2):228-235.
  https://doi.org/10.1002/cpt.1833
• Reutfors J, Cesta CE, Cohen JM, Bateman BT, Brauer R, Einarsdóttir K, Engeland A, Furu K, Gissler M, Havard A, Hernandez-Diaz S, Huybrechts KF, Karlstad Ø, Leinonen MK, Li J, Man KKC, Pazzagli L, Schaffer A, Schink T, Wang Z, Yu Y, Zoega H, Bröms G. Antipsychotic drug use in pregnancy: A multinational study from ten countries. Schizophrenia Research. 2020;220:106-115.
  https://doi.org/10.1016/j.schres.2020.03.048
• Schink T, Wentzell N, Dathe K, Onken M, Haug U. Estimating the beginning of pregnancy in German claims data: Development of an algorithm with a focus on the expected delivery date. Frontiers in Public Health. 2020;8:350.
  https://doi.org/10.3389/fpubh.2020.00350
• Wentzell N, Haug U, Schink T, Engel S, Liebentraut J, Linder R, Onken M, Schaefer C, Dathe K. Valproatverordnungen bei Mädchen und Frauen im gebärfähigen Alter in Deutschland: Untersuchung zeitlicher Trends basierend auf Versichertendaten. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2018;61(8):1022-1029.
  https://doi.org/10.1007/s00103-018-2768-1
• Wentzell N, Schink T, Haug U, Ulrich S, Niemeyer M, Mikolajczyk R. Optimizing an algorithm for the identification and classification of pregnancy outcomes in German claims data. Pharmacoepidemiology and Drug Safety. 2018;27(9):1005-1010.
  https://doi.org/10.1002/pds.4588
  https://repository.publisso.de/resource/frl%3A6417552

• Articles without peer review

• Wentzell N, Kollhorst B, Schink T. Verordnung von antiretroviralen Arzneimitteln bei Frauen im gebärfähigen Alter und in der Schwangerschaft. Bulletin zur Arzneimittelsicherheit - Informationen aus BfArM und PEI. 2024;1:10-15.
  https://www.bfarm.de/DE/Aktuelles/Publikationen/Bulletin/Ausgaben/_node.html
• Schink T, Princk C, Haug U. Risiko venöser Thromboembolien bei Einnahme von kombinierten hormonalen Kontrazeptiva. Bulletin zur Arzneimittelsicherheit - Informationen aus BfArM und PEI. 2021;2:13-16.
  https://www.bfarm.de/DE/Aktuelles/Publikationen/Bulletin/Ausgaben/_node.html

• Guidelines and reports

• The European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP), in collaboration with Pacurariu A, Kirchmayer U, Arana A, Schink T. Bias. Amsterdam, The Netherlands 2022.
  https://www.encepp.eu/standards_and_guidances/methodologicalGuide.shtml
• The European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP), in collaboration with Schink T, Hall G, Leacy F, Hallas J, Kurz X. The target trial emulation. Amsterdam, The Netherlands 2022.
  https://www.encepp.eu/standards_and_guidances/methodologicalGuide.shtml
• The European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP), in collaboration with Hall G, Schink T, Xie J. Triangulation. Amsterdam, The Netherlands 2022.
  https://www.encepp.eu/standards_and_guidances/methodologicalGuide.shtml
• The European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP), in collaboration with Hall G, Schink T, Li X. Use of an active comparator. Amsterdam, The Netherlands 2022.
  https://www.encepp.eu/standards_and_guidances/methodologicalGuide.shtml
• The European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP), in collaboration with Hall G, Schink T, Li X. Positive and negative control exposures and outcomes. Amsterdam, The Netherlands 2022.
  https://www.encepp.eu/standards_and_guidances/methodologicalGuide.shtml
• The European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP), in collaboration with Ehrenstein V, Margulis A, Schink T, De Vries C, Petersen I, Thurin N, Nordeng H. Annex 2 - Guidance on methods for the evaluation of medicines in pregnancy and breastfeeding. Amsterdam, The Netherlands 2022.
  https://www.encepp.eu/standards_and_guidances/methodologicalGuide.shtml
• The European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP), in collaboration with Hall G, Hallas J, Schink T. Definition and validation of drug exposure, outcomes and covariates. Amsterdam, The Netherlands 2022.
  https://www.encepp.eu/standards_and_guidances/methodologicalGuide.shtml
• The European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP), in collaboration with Hallas J, Ehrenstein V, Hall G, Schink T, Klungel O. Methods to address bias. Amsterdam, The Netherlands 2020.
  http://www.encepp.eu/standards_and_guidances/methodologicalGuide.shtml

• Books

• Sturkenboom MCJM, Schink T, editors. Databases for pharmacoepidemiological research. Cham: Springer; 2021.
  https://doi.org/10.1007/978-3-030-51455-6.

• Book chapters

• Enders D, Schink T, Stürmer T. Medicaid and Medicare. In: Sturkenboom MCJM, Schink T, editors. Databases for pharmacoepidemiological research. Cham: Springer. 2021. S. 231-242.
  https://doi.org/10.1007/978-3-030-51455-6_19
• Haug U, Schink T. German Pharmacoepidemiological Research Database (GePaRD). In: Sturkenboom MCJM, Schink T, editors. Databases for pharmacoepidemiological research. Cham: Springer. 2021. S. 119-124.
  https://doi.org/10.1007/978-3-030-51455-6_8

• Presentations at scientific meetings/conferences

• Schink T, Kollhorst B, Haug U. Emulating a target trial to estimate the causal effect of antiseizure medication on birthweight. 40th International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE), 24-28 August 2024, Berlin. (Abstract published in: Pharmacoepidemiology and Drug Safety. 2024;33(Suppl. 2):41)
• Wentzell N, Kollhorst B, Schink T. Use of HIV medication during pregnancy in Germany. 40th International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE), 24-28 August 2024, Berlin. (Abstract published in: Pharmacoepidemiology and Drug Safety. 2024;33(Suppl. 2):2)
• Schink T, Kollhorst B, Haug U. Antithyroid drug use before and during pregnancy: Assessment of switching patterns and changes over time. 39th International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE), 23-27 August 2023, Halifax, Canada. (Abstract published in: Pharmacoepidemiology and Drug Safety. 2023;32(Suppl. 1):8-9)
• Schink T, Wentzell N, Dathe K, Onken M, Haug U. Fetotoxicity of RAAS-inhibitors. 36th International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE), 16-17 September 2020, online presentation. (Abstract published in: Pharmacoepidemiology & Drug Safety. 2020;29(S3):3705)
• Schink T, Haug U. Estimation of the beginning of pregnancies ending in stillbirths. 35th International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE), 24-28 August 2019, Philadelphia, USA. (Abstract published in: Pharmacoepidemiology & Drug Safety. 2019;28(S2):479)

• Presentations at scientific meetings/conferences (invited)

• Schink T. Use of insurance data to study drug utilization in children with congenital malformations. Conference "Health and Education Outcomes of Children Across Europe with Congenital Anomalies" - EUROlinkCAT Conference, 7-8 April 2022, online presentation.
• Schink T. Establishment of a framework to study the utilization and safety of drugs during pregnancy in the German Pharmacoepidemiology Research Database (GePaRD). Basel Epidemiology Seminar (BES), 25 March 2021, online presentation.
• Schink T. Internal validation of outcomes in health databases. 8th Bordeaux Pharmacoepidemiology Festival, 21-23 May 2019, Bordeaux, France.

• Posters at scientific meetings/conferences

• Kollhorst B, Wentzell N, Niemeyer M, Haug U, Schink T. Identification of pregnancies without a recorded outcome in German claims data. 39th International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE), 23-27 August 2023, Halifax, Canada. (Abstract published in: Pharmacoepidemiology and Drug Safety. 2023;32(Suppl. 1):516-517)
• Schink T, Braitmaier M, Haug U. Long-term outcomes of children exposed to RAAS-inhibitors during pregnancy. 39th International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE), 23-27 August 2023, Halifax, Canada. (Abstract published in: Pharmacoepidemiology and Drug Safety. 2023;32(Supp. 1):527-528)
• Wentzell N, Kollhorst B, Schink T. Time trends of HIV treatment in girls and women of childbearing age in Germany. 39th International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE), 23-27 August 2023, Halifax, Canada. (Abstract published in: Pharmacoepidemiology and Drug Safety. 2023;32(Suppl. 1):523)

• Further Publications

• Master of Science in Epidemiology, Johannes Gutenberg-Universiät, Mainz Pharmakoepidemiology, since 2013
• Master of Science in Epidemiology, Ludwig-Maximilians-Universität, Munich Pharmakoepidemiology, since 2016