The department of Clinical Epidemiology addresses clinically relevant questions and examines them on the basis of epidemiological methods.
The overriding focus of the department is on the detection and prevention of
- Unfavorable courses of disease and,
- Drug risks.
We use mainly longitudinal data to answer the respective research questions and place particular emphasis on formative and vulnerable phases in the life course.
Research areas of the department
In the area of drug safety research, data from the German Pharmacoepidemiological Research Database (short GePaRD) is used to investigate the safety of new drugs after approval. The safety of medicines in special populations (e.g., the elderly, pregnant women) is also of interest.
Another research area is the epidemiology of neuropsychiatric disorders. The focus is on attention-deficit / hyperactivity disorder in children and adolescents, as well as on diseases of later adulthood like Parkinson's disease and related psychiatric disorders.
Translational cancer epidemiology concentrates on the (further) development and evaluation of strategies for the reduction of cancer incidence and mortality. The focus is on applied research, for example, colorectal cancer screening and cancer prevention in individuals with familial risk of cancer. The Bremen Cancer Registry is an important basis of this research focus.
Research databases of the department
The project-based German Pharmacoepidemiological Research Database (short GePaRD) was established by BIPS and is continuously maintained and expanded. It contains claims data from statutory health insurance (SHI) providers and comprises information from about 20 million insurance members since the year 2004.
The Bremen Cancer Registry is a clinical and population-based cancer registry that collects and evaluates data on cancer incidence, therapies, and mortality of all cancer patients diagnosed and / or treated in the federal state of Bremen.
The Bremen Mortality Index (BreMI) is a database providing all information recorded on death certificates of Bremen residents who have died since January 1, 1998. The information stored in the database includes all entries on the death certificates.
The list shows only projects for which the department has the main scientific responsibility. It only includes those projects that are currently running or that ended less than a year ago. The entries are sorted alphabetically.
- A multisite collaborative research program of observational studies to monitor the utilization and safety of dulaglutide in the EU
- Building an ecosystem for better monitoring and communicating of medication safety in pregnancy and breastfeeding
- Clinical and epidemiological cancer registry in Bremen
- Effects of bariatric procedures
- Evaluation of breast cancer mortality in the German Mammography Screening Program - Main Phase 1
- Further development, optimization and application of an algorithm for the detection of severe adverse drug reactions on the basis of claims data (WOLGA)
- Intervention study to ensure appropriate and safe drug utilization in children and adolescents
- Multimodal therapy of ADHD in health data claims
- Non-interventional post-authorization multi-database safety to characterize the risk of angioedema and other specific safety events of interest in association with use of Entresto® (sacubitril/valsartan) in audit patients with heart failure
- Post-authorization safety study (PASS) investigating the bleeding risk in patients treated with rivaroxaban
- Post-authorization safety study (PASS) on extrapyramidal symptoms in patients treated with Abilify Maintena® in Germany
- Post-authorization safety study (PASS) on roflumilast
- Post-authorization safety study (PASS) on the risk of severe hypersensitivity reactions in patients treated with intravenous iron
- Study to analyze regional differences in antibiotic prescriptions
- Studying drug safety during pregnancy based on routine data in Germany
- The BRodalumab Assessment of Hazards: A Multinational Safety (BRAHMS) study in electronic healthcare databases
- Utilization of surveillance colonoscopy in Germany: Current status and future concepts
Tel.: +49 (0)421 218-56860
Fax: +49 (0)421 218-56941
Tel.: +49 (0)421 218-56784
Tel.: +49 (0)421 218-56864
Fax: +49 (0)421 218-56821
Tel.: +49 (0)421 218-56863
Fax: +49 (0)421 218-56821