Statistical Modeling of Secondary and Registry Data Unit
The research interests of the Statistical Modeling of Secondary and Registry Data Unit are statistical methods to estimate the use, effects and risks of medications based on secondary data, and to estimate the progress as well as the survival of cancer. The unit has extensive statistical expertise for studies based on the pharmacoepidemiological research database that has been established at the BIPS and on the Bremen Cancer Registry. Methodological development is dedicated to the specifics of this database, i.e. the longitudinal data structure, the huge size of the population, the multitude of available covariates, the problem of unmeasured confounders and limitations, as well as the strengths of secondary data sources. Therefore, the main research focus is on methods for adjustment for confounders and analyses of linked data sources such as:
- Two-phase designs,
- Instrumental variable methods to account for unmeasured confounding,
- Marginal structural models to adjust for time-dependent confounders,
- New statistical methods for studies of comparative effectiveness and safety of medications.
The unit supports the department of Clinical Epidemiology regarding the design, conduct, and analysis of pharmacoepidemiological studies and contributes towards the development and maintenance of the pharmacoepidemiological research database and the Bremen Cancer Registry. Furthermore, the unit is involved in the Competence Network of Secondary and Registry Data of the German National Cohort.
Current Projects
Only currently running projects or those where publications are still in preparation or those that ended less than a year ago will be shown. The entries are sorted alphabetically.
- Cross-generational adverse drug effects
- Evaluation of an indirect record linkage method in an examplary study on the risk of cancer and cancer mortality in type 2 diabetes patients treated with different antidiabetics
- Health effects of cardiac fluoroscopy and modern radiotherapy in paediatrics
- Multimodal therapy of ADHD in health data claims
- Study to analyze regional differences in antibiotic prescriptions
- Studying drug safety during pregnancy based on routine data in Germany
- Use of routine data for pharmacovigilance in Germany: Method development and initial applications
- Utilization of surveillance colonoscopy in Germany: Current status and future concepts
Staff
Braitmaier, Malte
Tel.: +49 (0)421 218-56983
Fax: +49 (0)421 218-56941
braitmaier(at)leibniz-bips.de
Gabbert, Anja
Tel.: +49 (0)421 218-56934
Fax: +49 (0)421 218-56941
gabbert(at)leibniz-bips.de
Gesing, Nils Fabian
Tel.: +49 (0)421 218-56935
Fax: +49 (0)421 218-56941
gesing(at)leibniz-bips.de
Kollhorst, Bianca, Dr.
Tel.: +49 (0)421 218-56980
Fax: +49 (0)421 218-56941
kollhorst(at)leibniz-bips.de
Ludewig, Alina
Tel.: +49 (0)421 218-56882
Fax: +49 (0)421 218-56941
ludewig(at)leibniz-bips.de
Niemeyer, Marieke
Tel.: +49 (0)421 218-56876
Fax: +49 (0)421 218-56941
niemeyer(at)leibniz-bips.de
Schaffer, Inga
Tel.: +49 (0)421 218-56871
Fax: +49 (0)421 218-56941
schaffer(at)leibniz-bips.de
Viebrock, Jost
Tel.: +49 (0)421 218-56951
Fax: +49 (0)421 218-56941
viebrock(at)leibniz-bips.de
Volkmar, Philipp Alexander
Tel.: +49 (0)421 218-56948
Fax: +49 (0)421 218-56941
volkmar(at)leibniz-bips.de
Bianca Kollhorst
Head of Unit
Contact:
Dr. Bianca Kollhorst
Tel: +49 (0)421 218-56980
Fax: +49 (0)421 218-56941