Biometry and Data Management

Two years after the foundation of the institute, the Department of Biometry and Data Management has been established in 1983. In the beginning exclusively intended as a service unit supporting the other departments in planning, realising and evaluating epidemiological studies and ensuring an efficient IT infrastructure and database administration, it soon evolved into a department working on questions regarding methods and contents. Besides providing indispensable IT services, the department emphasises on harnessing and developing biometric methods for epidemiological issues.

With the increasing demands and opportunities due to Open Science and Open Data, the department's scope has expanded further. The expertise in this area is bundled and enhanced by the Cross-departmental Center for Research Data Infrastructure and Data Science in Epidemiology. Firstly, the center is dedicated to the further development of research data management and infrastructure in order to fully implement the FAIR principles. In this way, research data will be made findable, accessible, interoperable and reusable. Secondly, the center pools and analyses globally available datasets and develops statistical/computer science methods for such distributed data analyses.

Biometry

The institute has been in the position to assemble biometricians experienced in a wide range of epidemiological studies (case control, cohort, cross-sectional, longitudinal, incidence studies, etc.) as permanent staff. For specific research projects, a number of short-term employees as well as postgraduate students (usually financed by third parties) extend the range of methods employed in the department. In this context the department also offers the opportunity to write a PhD thesis.

Methods development

We are presently working on diverse topics: these include statistical issues related to the pharmacoepidemiologic research database (twophase studies, control for confounding - Statistical Modeling of Secondary and Registry Data Unit), improvement of statistical procedures in the analysis of gene-gene- and gene-environment interactions, the identification of biological pathways involved in the development of diseases and in the statistical modeling of pathways, accumulations of risk or critical time periods in life-course epidemiology (Statistical Methods for Genetics and Molecular Epidemiology Unit), statistical modeling of nutrition data and use of geographical information systems in epidemiologic studies (Statistical Modeling of Primary Data Unit). Furthermore, the department engages in the development of methods for causal inference, e.g. for instrumental variables or time-varying confounding (Statistical Methods for Causal Inference Research Group), and statistical machine learning (Emmy Noether Junior Research Group: Beyond Prediction - Statistical Inference with Machine Learning). With the improved accessibility of research data, development of methods for analysis and combining data, for example by means of record linkage or distributed analyses, is increasingly important.

Statistical support - quantitative methods consulting service

The department also houses a methods consultancy service that is used BIPS-internally as well as externally by other research institutions and scientifically working clinicians, primarily from Bremen and the surrounding region. Support is mainly requested in the planning phase of studies e.g. on the selection of the study design or on sample size calculations. Appropriate analysis methods are proposed and/or developed and support in the application of methods as well as in the interpretation and presentation of results is provided.

Within the inter-departmental working group GeTTCausal (GePaRD & Target Trials for Causal Inference), we combine expertise in secondary data analysis, causal inference, and clinical epidemiology to best analyze important causal questions based on GePaRD using the "target trial emulation" (TTE) approach.

Data Management

The department is responsible for providing an efficient IT infrastructure for the entire institute. This includes the procurement, installation, configuration, and maintenance of required software and hardware, provision of standard services such as email, file, or backup services, as well as the operation of systems necessary for research and research data management. The sensitivity of the data processed at the institute requires a high level of security, making IT security an integral part of the institute's IT infrastructure. By creating tools and methods for data collection and processing, metadata management, data preparation and quality assurance, and software development, the department enables the implementation of FAIR principles, especially in conducting epidemiological studies. This involves the central maintenance, management, and documentation of the institute's data holdings beyond the duration of the actual studies to ensure future usability of the data.

With expertise and the help of advanced tools in research data management and medical documentation, the department supports other departments in planning and conducting studies. Additionally, these tools and expertise are made available to external partners for use in studies. These tasks are consolidated in the IT, Data Management, and Medical Documentation Unit, whose staff have long-standing experience and are comprised of computer science, system administration and medical documentation specialists.

Staff

Bang, Christine Winther
bang(at)leibniz-bips.de

Bergen, Luca
bergen(at)leibniz-bips.de

Boekhoff, Svenja
Tel.: +49 (0)421 218-56978
boekhoff(at)leibniz-bips.de

Börnhorst, Claudia, Dr.
Tel.: +49 (0)421 218-56946
Fax: +49 (0)421 218-56941
boern(at)leibniz-bips.de

Boye, Friedrich
Tel.: +49 (0)421 218-56967
Fax: +49 (0)421 218-56941
boye(at)leibniz-bips.de

Braitmaier, Malte
Tel.: +49 (0)421 218-56983
Fax: +49 (0)421 218-56941
braitmaier(at)leibniz-bips.de

Brünings-Kuppe, Claudia
Tel.: +49 (0)421 218-56975
Fax: +49 (0)421 218-56941
bruening(at)leibniz-bips.de

Buck, Christoph, Dr.
Tel.: +49 (0)421 218-56944
Fax: +49 (0)421 218-56941
buck(at)leibniz-bips.de

Burk, Lukas
Tel.: +49 (0)421 218-56955
Fax: +49 (0)421 218-56941
burk(at)leibniz-bips.de

Cici, Selim
Tel.: +49 (0)421 218-56976
Fax: +49 (0)421 218-56941
cici(at)leibniz-bips.de

Desai, Krishna
desai(at)leibniz-bips.de

Didelez, Vanessa, Prof. Dr.
Tel.: +49 (0)421 218-56939
Fax: +49 (0)421 218-56941
didelez(at)leibniz-bips.de

Dijkstra, Louis
Tel.: +49 (0)421 218-56937
Fax: +49 (0)421 218-56941
dijkstra(at)leibniz-bips.de

Engelke, Tjark
Tel.: +49 (0)421 218-56793
engelke(at)leibniz-bips.de

Foraita, Ronja, Dr.
Tel.: +49 (0)421 218-56954
Fax: +49 (0)421 218-56941
foraita(at)leibniz-bips.de

Frielinghaus, Maria
Tel.: +49 (0)421 218-56791
Frielinghaus(at)leibniz-bips.de

Gabbert, Anja
Tel.: +49 (0)421 218-56934
Fax: +49 (0)421 218-56941
gabbert(at)leibniz-bips.de

Gadczikowske, Yvonne
Tel.: +49 (0)421 218-56889
Fax: +49 (0)421 218-56941
gadczikowske(at)leibniz-bips.de

Gesche, Stephan
Tel.: +49 (0)421 218-56958
Fax: +49 (0)421 218-56941
gesche(at)leibniz-bips.de

Gesing, Nils Fabian
Tel.: +49 (0)421 218-56935
Fax: +49 (0)421 218-56941
gesing(at)leibniz-bips.de

Golchian, Pegah
Tel.: +49 (0)421 218-56790
golchian(at)leibniz-bips.de

Hackbarth, Jan
Tel.: +49 (0)421 218-56898
Fax: +49 (0)421 218-56941
hackbarth(at)leibniz-bips.de

Höpner, Anna
Tel.: +49 (0)421 218-56969
Fax: +49 (0)421 218-56941
hoepner(at)leibniz-bips.de

Hummel-Bartenschlager, Willempje
Tel.: +49 (0)421 218-56979
Fax: +49 (0)421 218-56941
hummel(at)leibniz-bips.de

Intemann, Timm, Dr.
Tel.: +49 (0)421 218-56984
Fax: +49 (0)421 218-56921
intemann(at)leibniz-bips.de

Israel-Georgii, Sandra
Tel.: +49 (0)421 218-56976
Fax: +49 (0)421 218-56941
georgii(at)leibniz-bips.de

Janisch-Fabian, Stefan
Tel.: +49 (0)421 218-56968
Fax: +49 (0)421 218-56941
janisch(at)leibniz-bips.de

Kapar, Jan
Tel.: +49 (0)421 218-56929
Fax: +49 (0)421 218-56941
kapar(at)leibniz-bips.de

Koenen, Niklas
Tel.: +49 (0)421 218-56933
Fax: +49 (0)421 218-5641
koenen(at)leibniz-bips.de

Kollhorst, Bianca, Dr.
Tel.: +49 (0)421 218-56980
Fax: +49 (0)421 218-56941
kollhorst(at)leibniz-bips.de

Kutz, Dennis
Tel.: +49 (0)421 218-56959
Fax: +49 (0)421 218-56941
kutz(at)leibniz-bips.de

Langbein, Sophie
Tel.: +49 (0)421 218-56886
langbein(at)leibniz-bips.de

Lehmann, Carola
Tel.: +49 (0)421 218-56963
Fax: +49 (0)421 218-56941
lehmann(at)leibniz-bips.de

Lendle, Nadja
Tel.: +49 (0)421 218-56792
Fax: +49 (0)421 218-56941
lendle(at)leibniz-bips.de

Ludewig, Alina
Tel.: +49 (0)421 218-56882
Fax: +49 (0)421 218-56941
ludewig(at)leibniz-bips.de

Lünzmann, Hauke
Tel.: +49 (0)421 218-56973
Fax: +49 (0)421 218-56941
luenz(at)leibniz-bips.de

Mändle, Andreas, Dr.
Tel.: +49 (0)421 218-56794
maendle(at)leibniz-bips.de

Niemeyer, Marieke
Tel.: +49 (0)421 218-56876
Fax: +49 (0)421 218-56941
niemeyer(at)leibniz-bips.de

Peters, Manuela, Dr.
Tel.: +49 (0)421 218-56924
Fax: +49 (0)421 218-56941
mpeters(at)leibniz-bips.de

Pigeot, Iris, Prof. Dr.
Tel.: +49 (0)421 218-56942
Fax: +49 (0)421 218-56941
pigeot(at)leibniz-bips.de

Pohlabeln, Hermann, Dr.
Tel.: +49 (0)421 218-56947
Fax: +49 (0)421 218-56941
pohlabeln(at)leibniz-bips.de

Preyer-Reupsch, Stephanie
Tel.: +49 (0)421 218-56977
Fax: +49 (0)421 218-56941
reupsch(at)leibniz-bips.de

Prote, Ursel
Tel.: +49 (0)421 218-56974
Fax: +49 (0)421 218-56941
prote(at)leibniz-bips.de

Reest, Stefanie
Tel.: +49 (0)421 218-56750
Fax: +49 (0)421 218-56941
reest(at)leibniz-bips.de

Reineke, Achim, Dr.
Tel.: +49 (0)421 218-56966
Fax: +49 (0)421 218-56941
areineke(at)leibniz-bips.de

Renz, Fabian
Tel.: +49 (0)421 218-56971
Fax: +49 (0)421 218-56941
renz(at)leibniz-bips.de

Schaffer, Inga
Tel.: +49 (0)421 218-56871
Fax: +49 (0)421 218-56941
schaffer(at)leibniz-bips.de

Seifert, Bastian
Tel.: +49 (0)421 218-56927
Fax: +49 (0)421 218-56941
seifert(at)leibniz-bips.de

Siafaka, Rebekka
Tel.: +49 (0)421 218-56795
siafaka(at)leibniz-bips.de

Swenne, Annika
Tel.: +49 (0)421 218-56943
Fax: +49 (0)421 218-56941
swenne(at)leibniz-bips.de

Viebrock, Jost
Tel.: +49 (0)421 218-56951
Fax: +49 (0)421 218-56941
viebrock(at)leibniz-bips.de

Volkmar, Philipp Alexander
Tel.: +49 (0)421 218-56948
Fax: +49 (0)421 218-56941
volkmar(at)leibniz-bips.de

Voß, Sönke Knut
Tel.: +49 (0)421 218-56960
Fax: +49 (0)421 218-56941
voss(at)leibniz-bips.de

Wolter, Birgit
Tel.: +49 (0)421 218-56972
Fax: +49 (0)421 218-56941
wolter(at)leibniz-bips.de

Wright, Marvin N., Prof. Dr.
Tel.: +49 (0)421 218-56945
Fax: +49 (0)421 218-56941
wright(at)leibniz-bips.de

Wulf, Thore
Tel.: +49 (0)421 218-56949
Fax: +49 (0)421 218-56941
wulf(at)leibniz-bips.de

Zaja, Marcus
Tel.: +49 (0)421 218-56985
Fax: +49 (0)421 218-56941
zaja(at)leibniz-bips.de

Zhang, Jiumeng
zhang(at)leibniz-bips.de

Departmental News

Iris Pigeot
Head of Department (Scientific Director)

Contact:
Prof. Dr. Iris Pigeot
Tel: +49 (0)421 218-56742
Fax: +49 (0)421 218-56741

Email:
pigeot(at)leibniz-bips.de


Vanessa Didelez
Deputy Head of Department
(Head of Research Group)

Contact:
Prof. Dr. Vanessa Didelez
Tel: +49 (0)421 218-56939
Fax: +49 (0)421 218-56941

Email:
didelez(at)leibniz-bips.de



Office

Stefanie Brand
Tel.: +49 (0)421 218-56750
sbrand(at)leibniz-bips.de