Wissenschaftliche Publikationen
Es werden 50 aktuelle Zeitschriftenartikel in Zeitschriften mit Peer-Review-Verfahren angezeigt - sortiert nach dem Jahr und Zeitpunkt der Erfassung. Weitere Publikationen von BIPS-Beschäftigten können über die Suche rechts gefunden werden.
- Wang Y, Xi Y, Breitner-Busch S, Padberg F, Rachow A, Brenner H, Castell S, Harth V, Haug S, Khattak MNK, Koch-Gallenkamp L, Krist L, Lampl B, Lange B, Leitzmann M, Lieb W, Meinke-Franze C, Mikolajczyk R, Velásquez IM, Obi N, Övermöhle C, Pfrommer L, Pischon T, Rach S, Schmidt B, Willich SN, Huemer M-T, Peters A. Changes in mental health during the COVID-19 pandemic: An analysis of data from the German national cohort (NAKO) for the years 2014-2022. Deutsches Ärzteblatt International. 2026; 123(4):93-96.
https://doi.org/10.3238/arztebl.m2025.0218 - Rees-Punia E, Teras LR, Newton CC, Moore SC, I-Min L, Bates-Fraser L, Chiang KE, Bloodworth DE, Eliassen H, Mucci LA, Lynch B, Stampfer M, Song M, Brantley KD, Stopsack KH, Matthews CE, Patel AV. Leisure-time physical activity and cancer mortality among cancer survivors. JAMA Network Open. 2026; 9(2):e2556971.
https://doi.org/10.1001/jamanetworkopen.2025.56971 - Coyle-Asbil H, Osojnicki K, Robertson A, Baker R, Grigore M, Burr J, Buck C, Wright MN, Vallis LA. Predicting energy expenditure in preschool children using accelerometer and gyroscope data. Pediatric Exercise Science. 2026; (Epub 2026 Feb 10).
https://doi.org/10.1123/pes.2025-0014 - Golchian P, Kapar J, Watson DS, Wright MN. Missing value imputation with adversarial random forests-MissARF. Statistics in Medicine. 2026; 45:3-5.
https://doi.org/10.1002/sim.70379 - Bang CW, Witte J, Foraita R, Didelez V. Improving finite sample performance of causal discovery by exploiting temporal structure. Statistical Methods in Medical Research. 2026; (im Druck).
- Lampousi A-M, Zeng J, Löfvenborg JE, Carlsson S, Ludvigsson J. Red meat intake during pregnancy and childhood and risk of type 1 diabetes: Findings from the ABIS birth cohort. Diabetologia. 2026; (Epub 2026 Feb 7).
https://doi.org/10.1007/s00125-026-06671-z - Maier L, Sun Y, Kronberg J, Abner E, Estonian Biobank Research Team, Coley K, Marenholz I, Weiss S, Foraita R, Karramass T, Mykkänen J, Hernandez-Pacheco N, Wang C, Kitaba NT, Pechlivanis S, Bouzigon E, Tingskov Pedersen CE, Schoos A-MM, Curtin J, Kress S, Hernangomez-Laderas A, Foppiano F, Batini C, Bryant L, Homuth G, Gieger C, Gilles S, Lyytikäinen L-P, Rovio S, Pahkala K, Vernet R, Valenta R, Llop S, Torrent M, Böck A, Tang MLK, Schmidt-Weber CB, Metspalu A, Esko T, Sprikkelman AB, John C, Lee Y-A, Beyer K, Völzke H, Pigeot I, Traidl-Hoffmann C, Duijts L, Lu H, Raitakari OT, Lehtimäki T, Kähönen M, Tio CHL, Melén E, Pennell CE, Holloway JW, von Mutius E, Siroux V, Bønnelykke K, Custovic A, Simpson A, Schikowski T, Bilbao JR, Schaub B, Peters R, Kersten ETG, Vonk JM, Thiering E, Peters A, Koppelman GH, Standl M. Meta-analysis of genome-wide association studies of food allergy and IgE-sensitization. Journal of Allergy and Clinical Immunology. 2026; (Epub 2026 Feb 20).
https://doi.org/10.1016/j.jaci.2026.02.012 - Turroni S, Günther K, D'Amico F, Veidebaum T, Yiannis K, Molnár D, Lissner L, Foraita R, Barone M, Mora-MartÃnez C, Sanz Y, Fraterman A, Wolters M, Brigidi P, Candela M, Ahrens W, Rampelli S. Disrupted gut microbiome networks and unhealthy behaviors predict metabolic dysfunction in children and adolescents in the long term. iScience. 2026; 29(2):114763.
https://doi.org/10.1016/j.isci.2026.114763 - Slesinski SC, Bolte G, Zhuang S, Lakes T, Rehfuess E, Staab J, Bamberg F, Baurecht H, Becher H, Brenner H, Glaser N, Greiser KH, Günther K, Harth V, Heise J-K, Keil T, Klett-Tammen C, Leitzmann M, Lieb W, Meinke-Franze C, Mikolajczyk R, Moreno Velásquez I, Mueller U, Nagrani R, Obi N, Övermöhle C, Pischon T, Schikowski T, Schipf S, Schlett CL, Schmidt B, Schulze M, Tönnies T, Willich S, Peters A, Schneider A, Wolf K. Transportation noise and self-rated health: Evidence from the German National Cohort (NAKO). Environmental Research. 2026; 294:123885.
https://doi.org/10.1016/j.envres.2026.123885 - Kendzia B, Behrens T, Brüning T, Stang A, Jöckel K-H, Ahrens W. Risk of testicular cancer and exposure to welding fumes. European Journal of Public Health. 2026; (Epub 2026 Jan 10).
https://doi.org/10.1093/eurpub/ckaf255 - Espina C, Ritchie D, Riboli E, Kromhout H, Franceschi S, Lansdorp-Vogelaar I, Marteau TM, Bakogianni I, Vilahur N, Alberts CJ, Ivanus U, Feliu A, D'Souza E, Zeeb H, Mitrou G, Albreht T, Dillner J, Foucaud J, Manczuk M, Martin-Moreno JM, Medema RH, Murray D, Nagy P, Nicula F, Nyangasi M, Steindorf K, Tjønneland A, Cecchini M, Corbex M, Stepien M, Yared W, Carvalho AL, Schüz J. European code against cancer 5th edition: 14 ways you can help prevent cancer. The Lancet Regional Health - Europe. 2026; 63:101592.
https://doi.org/10.1016/j.lanepe.2026.101592 - Lakeberg M, Bachmann C, Hoffmann F, Jungmann T, Sandner M, Zeeb H, Kliem S, Brand T. Sex-specific associations between prenatal maternal mental health and child behavior problems at age 7: A (multi-center) longitudinal study of socially disadvantaged mother-child dyads. European Child & Adolescent Psychiatry. 2026; (Epub 2026 Feb 10).
https://doi.org/10.1007/s00787-026-02974-z - Loganathan GC, Buck C, Williams G, Veidebaum T, Tornaritis M, Molnár D, Miguel-Berges ML, Lissner L, Formisano A, De Henauw S, Baran J, Hebestreit A, Sina E. Associations between time spent with digital media and body image among European adolescents. BMC Pediatrics. 2026; (Epub 2026 Jan 31).
https://doi.org/10.1186/s12887-026-06551-w - D'Souza E, Ritchie D, Zeeb H, Schüz J, Espina C. European code against cancer, 5th edition: Using systems thinking to guide the dissemination of the European code against cancer. Molecular Oncology. 2026; 20(1):170-187.
https://doi.org/10.1002/1878-0261.70195 - Mantzari E, Brain K, Bessems KMHH, Bigaard J, Bouaoun L, D'Souza E, Espina C, Fonseca C, Feliu A, Petrova D, Ritchie D, Schüz J, Roggeri V, Zeeb H, Marteau TM. European code against cancer, 5th edition: To increase awareness of avoidable cancer risks in all socioeconomic groups. Molecular Oncology. 2026; 20(1):154-169.
https://doi.org/10.1002/1878-0261.70196 - Toes-Zoutendijk E, Arbyn M, Auvinen A, Baldwin D, Castells X, DeCensi A, Hofvind S, Ivanus U, Senore C, Thorat MA, van der Aalst C, Pinto ACPN, Bracchiglione J, Feliu A, Zeeb H, D'Souza E, Ritchie D, Espina C, Carvalho AL, Lansdorp-Vogelaar I. European code against cancer, 5th edition: Organised cancer screening programmes. Molecular Oncology. 2026; 20(1):134-153.
https://doi.org/10.1002/1878-0261.70197 - Albers CJ, Bloem P, de Sanjose S, Grabar S, Leja M, Malfertheiner P, Maticic M, Mégraud F, Negro F, Plummer M, Schim van der Loeff M, BalbÃn G, Salazar J, Zeeb H, Feliu A, D'Souza E, Ritchie D, Espina C, Franceschi S. European code against cancer, 5th edition: Cancer-causing infections and related interventions. Molecular Oncology. 2026; 20(1):96-116.
https://doi.org/10.1002/1878-0261.70172 - Hoek G, van Tongeren M, Röösli M, Jochems SH, Vilahur N, Albin M, Baldi I, Crowley Q, Fervers B, Greinert R, Consonni D, Feliu A, Zeeb H, Schüz J, D'Souza E, Ritchie D, Espina C, Kromhout H. European code against cancer, 5th edition: Outdoor and indoor air pollution and cancer. Molecular Oncology. 2026; 20(1):81-95.
https://doi.org/10.1002/1878-0261.70184 - Jochems SH, Vilahur N, van Tongeren M, Albin M, Baldi I, Consonni D, Crowley Q, Fervers B, Greinert R, Hoek G, Röösli M, Zeeb H, Schüz J, Feliu A, D'Souza E, Ritchie D, Espina C, Kromhout H. European code against cancer, 5th edition: Occupational exposures and cancer. Molecular Oncology. 2026; 20(1):68-80.
https://doi.org/10.1002/1878-0261.70174 - Ritchie D, Crowley Q, Greinert R, Albin M, Baldi I, Consonni D, Fervers B, Hoek G, Jochems SH, Röösli M, van Tongeren M, Vilahur N, Feliu A, Zeeb H, Schüz J, D'Souza E, Espina C, Kromhout H. European code against cancer, 5th edition: Ultraviolet radiation, radon and cancer. Molecular Oncology. 2026; 20(1):49-67.
https://doi.org/10.1002/1878-0261.70171 - Leitzmann M, Bakogianni I, Anderson AS, Bauld L, Fernández E, Morris S, Srour B, Vardavas C, Vlad I, Vulk S, Weijenberg M, Roqué I Figuls M, Rigau D, Feliu A, Zeeb H, Schüz J, D'Souza E, Ritchie D, Espina C, Riboli E. European code against cancer, 5th edition: Diet, excess body weight, physical activity, sedentary behavior, breastfeeding, and cancer. Molecular Oncology. 2026; 20(1):28-48.
https://doi.org/10.1002/1878-0261.70201 - Feliu A, Anderson AS, Bauld L, Fernández E, Leitzmann M, Morris S, Srour B, Vardavas C, Vlad I, Vuik S, Weijenberg M, Alvarado-Villacorta R, Canelo-Aybar C, Zeeb H, Schüz J, D'Souza E, Ritchie D, Espina C, Bakogianni I, Riboli E. European code against cancer, 5th edition: Tobacco and nicotine containing products, second-hand smoke, alcohol and cancer. Molecular Oncology. 2026; 20(1):6-27.
https://doi.org/10.1002/1878-0261.70177 - Becher H, Obi N, Brand T, Brenner H, Buschmann L, Fortner RT, Greiser KH, Harth V, Hoffmann W, Karch A, Keil T, Kluttig A, Krist L, Leitzmann M, Maun A, Mikolajczyk R, Nimptsch K, Pischon T, Schipf S, Schmidt B, Schultheiss UT, Schulze M, Zeeb H, Wiessner C. Participation behaviour of different migrant groups in breast cancer screening: Palpation of the breast and mammography - Results from the German National Cohort (NAKO). Journal of Migration and Health. 2026; 13:100397.
https://doi.org/10.1016/j.jmh.2026.100397 - Mulanje L, Brackmann K, Lübtow A, Zeeb H, Ahrens W, Marron M, Nagrani R. Maternal infection during pregnancy and the risk of childhood cancer: A systematic review and meta-analysis. BMC Medicine. 2026; 24:51.
https://doi.org/10.1186/s12916-026-04625-1 - Yuan L, Muli S, Goerdten J, Rattner J, Merdas M, Achaintre D, Foraita R, Wolters M, De Henauw S, Hunsberger M, Huybrechts I, Lissner L, Molnár D, Moreno LA, Russo P, Veidebaum T, Ahrens W, Nöthlings U, Keski-Rahkonen P, Oluwagbemigun K, Floegel A. Exploratory screening and replication of urinary biomarkers of fruit and vegetable intake in free-living European children and adolescents using untargeted metabolomics. The Journal of Nutrition. 2025; 156(2):101302.
https://doi.org/10.1016/j.tjnut.2025.101302 - Vahid F, Loyola-Leyva A, Tur J, Bouzas C, Devaux Y, Malisoux L, GarcÃa S, De Carvalho M, Ródenas-Munar M, Turner J, Lamy E, Pérez-Jiménez M, Ravn-Haren G, Andersen R, Forberger S, Nagrani R, Onorati MG, Bonetti GG, Rodrigues D, Bohn T. Multimodal (bio) markers and risk of obesity: A comprehensive scoping review. Advances in Nutrition. 2026; 17(2):100579. (Epub 2025 Dec 24).
https://doi.org/10.1016/j.advnut.2025.100579 - GarcÃa S, Ródenas-Munar M, Bohn T, Kemperman A, Rodrigues D, Evers S, Lamy E, Pérez-Jiménez M, Forberger S, Onorati MG, Devecchi A, de Magistris T, Halimi J, Ivanova Y, Doychinov B, Bouzas C, Tur J. Empowering healthy lifestyle behavior through personalized intervention portfolios using a healthy lifestyle recommender system to prevent and control obesity in young adults: Pilot study protocol from the HealthyW8 project. Journal of Personalized Medicine. 2025; 15(12):625.
https://doi.org/10.3390/jpm15120625 - Zavala GA, Asim M, Ayub A, Ahmad AMR, Pillai AP, Pavlou E, Sharma A, Khan BA, Shakoor H, Mansukoski L, Garcia Obregon OP, Khan U, Khan Z, Rehman A, Un Nisa B, Bibi H, Iqbal R, Gill S, Ashfaq U, Khan FU, Bhutta Z, Forberger S, Siddiqi K, Suhrcke M, Walker S, Samad Z, Afaq S. Protocol: Effectiveness of interventions for the prevention and treatment of obesity in children and adolescents from low- and middle-income countries: A systematic review and meta-analysis. Campbell Systematic Reviews. 2025; 21(4):e70081.
https://doi.org/10.1002/cl2.70081 - Jung D, Branscheidt S, Wittenberg I, Schmidt-Pokrzywniak A, Piontek D, Brand T, Klora M, Zeissig SR, Beck N, Feller A, Hermann S, Kanbach J, Luttmann S, Pritzkuleit R, Braun B, Erb C, Kusche H, Robers G, Weitmann K, Abnaof K, Kim-Wanner S-Z, Reil D, von Rüsten A, Oesterling F, Stang A, Ronckers CM, Bremensdorfer C, Justenhoven C, Hasenburg A. Epidemiology and treatment of malignant ovarian germ cell and sex cord stromal tumors in Germany: A population-based cancer registry study from 2016-2021. Scientific Reports. 2025; 15:44145.
https://doi.org/10.1038/s41598-025-32998-5 - Lübtow A, Marron M, Nagrani R, Mulanje L, Ahrens W, Brackmann K. Prenatal exposure to medication and risk of childhood cancer: A systematic review and meta-analysis. BMC Cancer. 2025; 25:1841.
https://doi.org/10.1186/s12885-025-15316-0 - Benson J, Lakeberg M, Palmer T, Brand T, Zeeb H. Participatory co-creation of a smartphone application using girl-centered-design to support adolescent girls' health: Barriers, enablers and lessons learned across six countries. Digital Health. 2026; (im Druck).
- Schepan ML, Ahrens W, Altgeld T, Busse H, Haines J, Rataj E, Swenne A, Wolters M, Zeeb H, Brand T. Implementing a family-based intervention to promote healthy family routines in deprived neighborhoods: A feasibility study from Bremen, Germany. BMC Public Health. 2025; 25:4344.
https://doi.org/10.1186/s12889-025-25532-9 - Wang M, Wu Y, Li M, Guan H, Gao X, Zhang P, Wang Y, Nur E, Hebestreit A, Wang H-J, Sun L, Wang H. Live-streamed exercise intervention in pregnant women with MASLD (Live-MALSD): Protocol for a randomized controlled trial. Annals of the New York Academy of Sciences. 2026; 1556(1):e70208.
https://doi.org/10.1111/nyas.70208 - Princk C, Wentzell N, Onken M, Thöne K, Kollhorst B, Schaefer C, Dathe K, Haug U. Treatment with tumor necrosis factor inhibitors during pregnancy and occurrence of severe infections among exposed infants in Germany. BMC Pregnancy and Childbirth. 2025; 26:78.
https://doi.org/10.1186/s12884-025-08590-0 - Gill S, Christianson L, Dreger S, Zeeb H. Internal contamination with transuranium radionuclides: Systematic review on assessment methods and diethylenetriamine pentaacetate (DTPA) treatment. Disaster Medicine and Public Health Preparedness. 2025; 19:e346.
https://doi.org/10.1017/dmp.2025.10224 - Hayes G, Buck C, Cardon G, Cimler R, Elavsky S, Fezeu LK, Harrington JM, Kühnová J, Oppert J-M, Sigcha L, Van de Ven P, Vetrovsky T, Woods C, Hebestreit A, Donnelly A. Standardized methods for evaluating physical and eating behaviours: The wearable sensor - Assessment of physical and eating Behaviours "WEALTH" project. JMIR Research Protocols. 2026; (Epub 2025 Dec 10).
https://doi.org/10.2196/70186 - Swenne A, Intemann T, Moreno LA, Pigeot I. Federated generalized additive models for location, scale and shape. BMC Medical Research Methodology. 2025; 25:276.
https://doi.org/10.1186/s12874-025-02735-7 - König LM, Forbes CC, Busse H, DeSmet A, Szinay D, Wan J, Guo Z, Smit ES. Inequalities in exclusively mobile interventions targeting weight-related behaviors: Systematic review of observational studies. Obesity Reviews. 2026; (Epub 2025 Dec 6).
https://doi.org/10.1111/obr.70057 - Iqbal K, Chatziangelousi E, Wolters M, Intemann T, Englert K, Hebestreit A, Aleksandrova K. Reference curves for metabolic syndrome indicators in children and adolescents: A global systematic review. Current Obesity Reports. 2026; 15(1):3. (Epub 2026 Jan 5).
https://doi.org/10.1007/s13679-025-00679-z - Liu J, Tran D, Xue L, Wiley BJ, Vlasschaert C, Watson CJ, MacGregor HAJ, Zong X, Chan ICC, Das I, Uddin MM, Niroula A, Griffin G, Ebert BL, Mack T, Pershad Y, Sharber B, Berger M, Zehir A, Ptashkin R, Levine RL, Papaemmanuil E, Joseph V, Gao T, Kemel Y, Mandelker D, Stopsack KH, Pharoah PD, Mukherjee S, Ding L, Cao Y, Walter MJ, Blundell JR, Chatterjee N, Offit K, Godley LA, Link DC, Stadler ZK, Bick AG, Natarajan P, Bolton KL. Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy. Nature Genetics. 2025; 57(8):1872-1880.
https://doi.org/10.1038/s41588-025-02250-x - Bouchan J, Fezeu LK, Vetrovsky T, Elavsky S, Delestre F, De Vylder F, Buck C, Hebestreit A, Harrington JM, Hayes G, Donnelly A, Oppert J-M, Cardon G, on behalf of the WEALTH consortium. Acceptability of intensive ambulatory assessment combining four wearable sensors and Ecological Momentary Assessment to assess physical and eating behaviors in adults: The WEALTH Project. Journal for the Measurement of Physical Behaviour. 2026; 9(1):jmpb.2025-0025.
https://doi.org/10.1123/jmpb.2025-0025 - Zhang Y-X, Albers R, Chen Y-T, Steineck G, Kellen E, Johnson KC, Lu C-M, Pohlabeln H, La Vecchia C, Porru S, Carta A, Polesel J, Bosetti C, Jiang X, Tang L, Marshall J, Karagas MR, Zhang Z-F, Taylor JA, Zeegers MP, Wesselius A, Yi-Wen Yu E. The association between tea consumption and bladder cancer risk based on the bladder cancer epidemiology and nutritional determinants (BLEND) international consortium. Nutrition and Cancer. 2025; 77(6):687-698.
https://doi.org/10.1080/01635581.2025.2488063 - Thong MS-Y, Doege D, Koch-Gallenkamp L, Bertram H, Eberle A, Holleczek B, Nennecke A, Waldmann A, Zeissig SR, Pritzkuleit R, Brähler E, Brenner H, Arndt V. Fatigue in long-term cancer survivors - Prevalence, associated factors, and mortality: A prospective population-based study. British Journal of Cancer. 2025; 133(6):831-843.
https://doi.org/10.1038/s41416-025-03116-z - Rhodes K, Garbe E, Müllerová H, Ekwaru P, Kossack N, Baak B, Lobier M, Hawkins NM, Nordon C. Framework for exploration of statistical heterogeneity in multi-database studies: A case study using EXACOS-CV studies. Clinical Epidemiology. 2025; 17:551-565.
https://doi.org/10.2147/CLEP.S520168 - Piedvache A, Rashed WM, Petridou E(boN-S), Mueller BA, Bonaventure A, Clavel J, de Smith AJ, Scheurer ME, Dockerty JD, Metayer C, Wiemels J, Kang AY, Heck JE, Hansen J, Mejia-Arangure JM, Sepúlveda-Robles OA, Pombo-de-Oliveira MS, Infante-Rivard C, Roman E, Erdmann F, Schüz J, Hangai M, Morisaki M, Morisaki N, Doody DR, Flores-Lujano J, Chow EJ, Sergentanis TN, Polychonopoulou S, Spector LG, Urayama KY. Maternal prenatal infection and childhood leukaemia: A childhood cancer and leukemia international consortium (CLIC) meta-analysis. International Journal of Epidemiology. 2025; 54(5):dyaf167.
https://doi.org/10.1093/ije/dyaf167 - Louro J, Kampitsi C-E, Mogensen H, Erdmann F, Modig K, Nilsson A, Heyman M, Hasle H, Krøyer A, Kenborg L, Hjalgrim H, Feychting M, Tettamanti G. COVID-19 infection and severity among childhood cancer survivors in Denmark and Sweden: A register-based cohort study with matched population and sibling comparisons. The Lancet Regional Health - Europe. 2025; 55:101363.
https://doi.org/10.1016/j.lanepe.2025.101363 - Fischer S, Zobolas J, Sonabend R, Becker M, Lang M, Binder M, Schneider L, Burk L, Schratz P, Jaeger BC, Lauer SA, Kapsner LA, Mücke M, Wang Z, Pulatov D, Ganz K, Funk H, Harutyunyan L, Camilleri P, Kopper P, Bender A, Zhou B, German N, Koers L, Nazarova A, Bischl B. mlr3extralearners: Expanding the mlr3 ecosystem with community-driven learner integration. The Journal of Open Source Software. 2025; 10(115):8331.
https://doi.org/10.21105/joss.08331 - Intemann T, Kaulke K, Kipker D-K, Lettieri V, Stallmann C, Schmidt CO, Bialke M, Hampf C, Stahl D, Lablans M, Kraywinkel K, Bartholomäus S, Näher A-F, Tremper G, Lambarki M, March S, Prasser F, Haber AC, Drepper J, Schlünder I, Kirsten T, Pigeot I, Sax U, Buchner B, Semler SC, Ahrens W. Verbesserung des Record Linkage für die Gesundheitsforschung in Deutschland: Wie können Defizite behoben werden?. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2025; 68:1440-1449.
https://doi.org/10.1007/s00103-025-04153-y - Schink T, Braitmaier M, Dathe K, Haug U, Schaefer C, Thöne K, Onken M. Postnatal and long-term outcomes after in utero exposure to RAAS inhibitors: Cohort study based on German claims data. Pediatric Nephrology. 2026; (Epub 2025 Dec 17).
https://doi.org/10.1007/s00467-025-07101-9 - Brandes M, Sell L, Thies S, Brandes B, Busse H, Zeeb H. Bremen active schools: Promoting physical activity in primary school children. Public Health Forum. 2025; 33(3):237-240.
https://doi.org/10.1515/pubhef-2025-0048