Prof. Dr. sc. hum. Ulrike Haug

• Epidemiologie und Früherkennung des kolorektalen Karzinoms, Evaluation von Testverfahren und Programmen zur Krebsfrüherkennung, Krebsprävention in Risikogruppen, Pharmakoepidemiologie

• Deutsche Gesellschaft für Epidemiologie (DGEpi)
• International Society for Pharmacoepidemiology (ISPE)
• Vaccine Monitoring Collaboration for Europe (VAC4EU)
• Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie (GAA)

• Fehlversorgung bzgl. Kontroll-Koloskopien in Deutschland: Ausmaß, Determinanten und Konzipierung von Lösungsansätzen (KOL-OPT)
• Untersuchungen zur Arzneimitteltherapiesicherheit in der Schwangerschaft basierend auf Routinedaten in Deutschland

Ausgewählte BIPS-Veröffentlichungen

• Zeitschriftenartikel mit peer-review

• Braitmaier M, Schwarz S, Didelez V, Haug U. Misleading and avoidable: Design-induced biases in observational studies evaluating cancer screening--the example of site-specific effectiveness of screening colonoscopy. American Journal of Epidemiology. 2025;
  https://doi.org/10.1093/aje/kwaf069
• Foroutan F, Vandvik PO, Helsingen LM, Kalager M, Rutter M, Selby K, Pilonis ND, Anderson JC, McKinnon A, Fuchs JM, Quinlan C, Buskermolen M, Senore C, Wang P, Sung JJY, Haug U, Bjerkelund S, Triantafyllou K, Shung DL, Halvorsen N, McGinn T, Hafver TL, Reinthaler V, Guyatt G, Agoritsas T, Sultan S. Computer aided detection and diagnosis of polyps in adult patients undergoing colonoscopy: A living clinical practice guideline. The BMJ. 2025;388:e082656.
  https://doi.org/10.1136/bmj-2024-082656
• Hornschuch M, Schwarz S, Haug U. High utilization of colonoscopy and fecal occult blood testing for screening or diagnostic purposes in Germany: A longitudinal analysis. European Journal of Cancer Prevention. 2025;
  https://doi.org/10.1097/CEJ.0000000000000956
• Ramin T, Peter J-U, Schneider M, Heinze M, Riedel O, Langbein S, Haug U, Zolk O. Age and sex differences in outpatient antipsychotic prescriptions for schizophrenia: A claims data study. European Archives of Psychiatry and Clinical Neuroscience. 2025;275(5):1403-1417.
  https://doi.org/10.1007/s00406-024-01867-z
• Hornschuch M, Schwarz S, Haug U. Proportion and characteristics of screen-detected and non-screen-detected colorectal cancers in Germany. Acta Oncologica. 2024;63(1):924-931.
  https://doi.org/10.2340/1651-226X.2024.40234
• Princk C, Kollhorst B, Haug U. Use of leflunomide among girls and women of childbearing age and occurrence of leflunomide-exposed pregnancies in Germany. Reproductive Toxicology. 2024;125:108573.
  https://doi.org/10.1016/j.reprotox.2024.108573
• Reinold J, Kollhorst B, Wentzell N, Platzbecker K, Haug U. Use of isotretinoin among girls and women of childbearing age and occurrence of isotretinoin-exposed pregnancies in Germany: A population-based study. PLoS Medicine. 2024;21(1):e1004339.
  https://doi.org/10.1371/journal.pmed.1004339
• Riedel O, Braitmaier M, Dankhoff M, Haug U, Klein M, Zachariassen W, Hoyer J. Alcohol use disorders after bariatric surgery: A study using linked health claims and survey data. International Journal of Obesity. 2024;48(11):1656-1663.
  https://doi.org/10.1038/s41366-024-01606-3
• Rischke N, Kanbach J, Haug U. Age differences in the treatment of lung cancer: A cohort study among 42,000 patients from Germany. Journal of Cancer Research and Clinical Oncology. 2024;150:503.
  https://doi.org/10.1007/s00432-024-06025-5
• Scholle O, Rasmussen L, Reilev M, Viebrock J, Haug U. Comparative analysis of outpatient antibiotic prescribing in early life: A population-based study across birth cohorts in Denmark and Germany. Infectious Diseases and Therapy. 2024;13(2):299-312.
  https://doi.org/10.1007/s40121-024-00916-3
• Schwarz S, Braitmaier M, Pox C, Kollhorst B, Didelez V, Haug U. 13-year colorectal cancer risk after lower-quality, higher-quality and no screening colonoscopy: A cohort study. Journal of Clinical Epidemiology. 2024;176:111571.
  https://doi.org/10.1016/j.jclinepi.2024.111571
• Amann U, Wentzell N, Kollhorst B, Haug U. Prescribing of endothelin receptor antagonists and riociguat in women of childbearing age in a large German claims database study. Reproductive Toxicology. 2023;119:108415.
  https://doi.org/10.1016/j.reprotox.2023.108415
  https://repository.publisso.de/resource/frl:6452989
• Bresalier RS, Senore C, Young GP, Allison J, Benamouzig R, Benton S, Bossuyt PM, Caro L, Carvalho B, Chiu H-M, Coupé VM, de Klaver W, de Klerk CM, Dekker E, Dolwani S, Fraser CG, Grady W, Guittet L, Gupta S, Halloran SP, Haug U, Hoff G, Itzkowitz S, Kortlever T, Koulaouzidis A, Ladabaum U, Lauby-Secretan B, Leja M, Levin B, Levin TR, Macrae F, Meijer GA, Melson J, O'Morain C, Parry S, Rabeneck L, Ransohoff DF, Sáenz R, Saito H, Sanduleanu-Dascalescu S, Schoen RE, Selby K, Singh H, Steele RJ, Sung JJY, Symonds EL, Winawer SJ. An efficient strategy for evaluating new non-invasive screening tests for colorectal cancer: The guiding principles. Gut. 2023;72(10):1904-1918.
  http://dx.doi.org/10.1136/gutjnl-2023-329701
• Haug U, Kollhorst B, Schink T, Thöne K, Dathe K, Schaefer C, Onken M. Investigating drug safety in pregnancy based on the German Pharmacoepidemiological Research Database (GePaRD): A proof-of-concept analysis on the association between valproate and spina bifida. Pharmacoepidemiology and Drug Safety. 2023;32(2):148-157.
  https://doi.org/10.1002/pds.5573
• Heinig M, Schäfer W, Langner I, Zeeb H, Haug U. German mammography screening program: Adherence, characteristics of (non-)participants and utilization of non-screening mammography - A longitudinal analysis. BMC Public Health. 2023;23:1678.
  https://doi.org/10.1186/s12889-023-16589-5
• Heinze F, Czwikla J, Heinig M, Langner I, Haug U. German mammography screening program: Program sensitivity between 2010 and 2016 estimated based on German health claims data. BMC Cancer. 2023;23:852.
  https://doi.org/10.1186/s12885-023-11378-0
• Neubert A, Toni I, König J, Malonga Makosi D, Mildenberger P, Romanos M, Bertsche A, Bertsche T, Dahlem P, Egberts K, Erdlenbruch B, Fekete S, Haug U, Horneff G, Hübler A, Kiess W, Neininger MP, Niehues T, Sachs B, Schettler KF, Schreeck F, Steimle T, Wenzl T, Wirth S, Zepp F, Schwab M, Urschwitz MS, Rascher W, im Namen des KiDSafe Konsortium. A complex intervention to prevent medication-related hospital admissions: Results of the stepped-wedge cluster-randomized trial KiDSafe in pediatrics. Deutsches Ärzteblatt International. 2023;120(25):425-431.
  https://doi.org/10.3238/arztebl.m2023.0123
• Rach S, Kühne L, Zeeb H, Ahrens W, Haug U, Pohlabeln H. Mild COVID-19 infection associated with post-COVID-19 condition after 3 months – A questionnaire survey. Annals of Medicine. 2023;55(1):2226907.
  https://doi.org/10.1080/07853890.2023.2226907
• Reilev M, Jensen PB, Ranch LS, Egenberg A, Furu K, Gembert K, Hägg D, Haug U, Karlstad Ø, Reutfors J, Schäfer W, Schwarz S, Smits E, Holthuis E, Herings R, Trifirò G, Kirchmayer U, Cesare Rosa A, Belleudi V, Gini R, Støvring Henrik, Hallas J. Methodology of the brodalumab assessment of hazards: A multicentre observational safety (BRAHMS) study. BMJ Open. 2023;13:e066057.
  https://doi.org/10.1136/bmjopen-2022-066057
• Reinold J, Kollhorst B, Temme HL, Wentzell N, Haug U. Use of acitretin among girls and women of childbearing age and occurrence of acitretin-exposed pregnancies in Germany. Clinical Drug Investigation. 2023;43(11):865-872.
  https://doi.org/10.1007/s40261-023-01314-2
• Riedel O, Viebrock J, Haug U. Overall survival in 92,991 colorectal cancer patients in Germany: Differences according to type of comorbidity. Acta Oncologica. 2023;62(12):1931-1938.
  https://doi.org/10.1080/0284186X.2023.2282120
• Schwarz S, Hornschuch M, Pox C, Haug U. Colorectal cancer after screening colonoscopy: 10-year incidence by site and detection rate at first repeat colonoscopy. Clinical and Translational Gastroenterology. 2023;14(1):e00535.
  https://doi.org/10.14309/ctg.0000000000000535
• Schwarz S, Hornschuch M, Pox C, Haug U. Polyp detection rate and cumulative incidence of post-colonoscopy colorectal cancer in Germany. International Journal of Cancer. 2023;152(8):1547-1555.
  https://doi.org/10.1002/ijc.34375
• Voss A, Kollhorst B, Platzbecker K, Amann U, Haug U. Risk profiles of new users of oral anticoagulants between 2011 and 2019 in Germany. Clinical Epidemiology. 2023;15:827-837.
  https://doi.org/10.2147/CLEP.S405585
• Voss A, Smits E, Swart KM, Balabanova Y, Brobert G, Suzart-Woischnik K, Herings R, Schink T, Haug U. Time trends in patient characteristics of new rivaroxaban users with atrial fibrillation in Germany and the Netherlands. Drugs - Real World Outcomes. 2023;10(2):215-224.
  https://doi.org/10.1007/s40801-022-00350-2
• Wentzell N, Kollhorst B, Reinold J, Haug U. Use of methotrexate in girls and women of childbearing age, occurrence of methotrexate-exposed pregnancies and their outcomes in Germany: A claims data analysis. Clinical Drug Investigation. 2023;43(2):109-117.
  https://doi.org/10.1007/s40261-022-01227-6
• Willame C, Dodd C, Duran C, Elbers R, Gini R, Bartolini C, Paoletti O, Wang L, Ehrenstein V, Kahlert J, Haug U, Schink T, Diez-Domingo J, Mira-Iglesias A, Carreras JJ, Vergara-Hernández C, Giaquinto C, Barbieri E, Stona L, Huerta C, Martin-Perez M, Garcia-Poza P, de Burgos A, Martinez-Gonzalez M, Bryant V, Villalobos F, Pallejà-Millán M, Aragon M, Carreras JJ, Souverein P, Thurin N, Weibel D, Klungel O, Sturkenboom MCJM. Background rates of 41 adverse events of special interest for COVID-19 vaccines in 10 European healthcare databases - An ACCESS cohort study. Vaccine. 2023;41(1):251-262.
  https://doi.org/10.1016/j.vaccine.2022.11.031
• Asendorf M, Reinold J, Schink T, Kollhorst B, Haug U. Abbildbarkeit des sozioökonomischen Status in der pharmakoepidemiologischen Forschungsdatenbank GePaRD: Beschreibung und Anwendung am Beispiel des Zusammenhangs mit Adipositas. GMS Medizinische Informatik, Biometrie und Epidemiologie. 2022;18(1):Doc02.
  https://doi.org/10.3205/mibe000235
• Braitmaier M, Kollhorst B, Heinig M, Langner I, Czwikla J, Heinze F, Buschmann L, Minnerup H, García-Albéniz X, Hense H-W, Karch A, Zeeb H, Haug U, Didelez V. Effectiveness of mammography screening on breast cancer mortality - A study protocol for emulation of target trials using German health claims data. Clinical Epidemiology. 2022;14:1293-1303.
  https://doi.org/10.2147/CLEP.S376107
• Braitmaier M, Schwarz S, Kollhorst B, Senore C, Didelez V, Haug U. Screening colonoscopy similarly prevented distal and proximal colorectal cancer: A prospective study among 55-69-year-olds. Journal of Clinical Epidemiology. 2022;149:118-126.
  https://doi.org/10.1016/j.jclinepi.2022.05.024
• Dengler R, Straub N, Bredow L, Becker J, Hornschuch M, Riedel O, Haug U, Waldeyer K, Hermes-Moll K, Osburg S, Martin J, Walawgo T, Heidt V, Froschauer S. Ambulante spezialfachärztliche Versorgung (ASV): Eine multiperspektivische Studie zu Status quo, Herausforderungen und Perspektiven. Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen. 2022;174:70-81.
  https://doi.org/10.1016/j.zefq.2022.06.003
• Heinig M, Heinze F, Schwarz S, Haug U. Initial and ten-year treatment patterns among 11,000 breast cancer patients undergoing breast surgery - An analysis of German claims data. BMC Cancer. 2022;22:130.
  https://doi.org/10.1186/s12885-022-09240-w
• Hornschuch M, Schwarz S, Haug U. 10-year prevalence of diagnostic and screening colonoscopy use in Germany: A claims data analysis. European Journal of Cancer Prevention. 2022;31(6):497-504.
  https://doi.org/10.1097/CEJ.0000000000000736
• Lansdorp-Vogelaar I, Meester R, de Jonge L, Buron A, Haug U, Senore C. Risk-stratified strategies in population screening for colorectal cancer. International Journal of Cancer. 2022;150(3):397-405.
  https://doi.org/10.1002/ijc.33784
• Peters A, on behalf of the GNC consortium, Greiser KH, Göttlicher S, Ahrens W, Albrecht M, Bamberg F, Bäringhausen T, Becher H, Berger K, Beule A, Boeing H, Bohn B, Bohnert K, Braun B, Brenner H, Bülow R, Castell S, Damms-Machado A, Dörr M, Ebert N, Ecker M, Emmel C, Fischer B, Franzke C-W, Gastell S, Giani G, Günther M, Günther K, Günther K-P, Haerting J, Haug U, Heid I, Heier M, Heinemeyer D, Hendel T, Herbolsheimer F, Hirsch J, Hoffmann W, Holleczek B, Hölling H, Hörlein A, Jöckel K-H, Kaaks R, Karch A, Karrasch S, Kartschmit N, Kauczor H-U, Keil T, Kemmling Y, Klee B, Klüppelholz B, Kluttig A, Kofink L, Köttgen A, Kraft D, Krause G, Kretz L, Krist L, Kühnisch J, Kuß O, Legath N, Lehnich A-T, Leitzmann M, Lieb W, Linseisen J, Löffler M, Macdonald A, Maier-Hein K, Mangold N, Meinke-Franze C, Meisinger C, Melzer J, Mergarten B, Michels K, Mikolajczyk R, Moebus S, Mueller U, Nauck M, Niendorf T, Nikolaou K, Obi N, Ostrzinski S, Panreck L, Pigeot I, Pischon T, Pschibul-Thamm I, Rathmann W, Reineke A, Roloff S, Rujescu D, Rupf S, Sander O, Schikowski T, Schipf S, Schirmacher P, Schlett CL, Schmidt B, Schmidt G, Schmidt M, Schöne G, Schulz H, Schulze MB, Schweig A, Sedlmeier AM, Selder S, Six-Merker J, Sowade R, Stang A, Stegle O, Steindorf K, Stübs G, Swart E, Teismann H, Thiele I, Thierry S, Ueffing M, Völzke H, Waniek S, Weber A, Werner N, Wichmann H-E, Willich SN, Wirkner K, Wolf K, Wolff R, Zeeb H, Zinkhan M, Zschocke J. Framework and baseline examination of the German National Cohort (NAKO). European Journal of Epidemiology. 2022;37(10):1107-1124.
  https://doi.org/10.1007/s10654-022-00890-5
• Platzbecker K, Schäfer W, Haug U. Does the socioeconomic status differ between users of potentially NDMA-contaminated generic valsartan and users of brand-name valsartan in Germany. GMS Medizinische Informatik, Biometrie und Epidemiologie. 2022;18(1):Doc3.
  https://doi.org/10.3205/mibe000236
• Platzbecker K, Wentzell N, Kollhorst B, Haug U. Fingolimod, teriflunomide and cladribine for the treatment of multiple sclerosis in women of childbearing age: Description of drug utilization and exposed pregnancies in Germany. Multiple Sclerosis and Related Disorders. 2022;67:104184.
  https://doi.org/10.1016/j.msard.2022.104184
  https://repository.publisso.de/resource/frl:6435355
• Reinold J, Braitmaier M, Riedel O, Haug U. Potential of health insurance claims data to predict fractures in older adults: A prospective cohort study. Clinical Epidemiology. 2022;14:1111-1122.
  https://doi.org/10.2147/CLEP.S379002
• Schink T, Princk C, Braitmaier M, Haug U. Use of combined oral contraceptives and risk of venous thromboembolism in young women: A nested case-control analysis using German claims data. BJOG: An International Journal of Obstetrics & Gynaecology. 2022;129(13):2107-2116.
  https://doi.org/10.1111/1471-0528.17268
• Scholle O, Asendorf M, Buck C, Grill S, Jones C, Kollhorst B, Riedel O, Schüz B, Haug U. Regional variations in outpatient antibiotic prescribing in Germany: A small area analysis based on claims data. Antibiotics. 2022;11(7):836.
  https://doi.org/10.3390/antibiotics11070836
• Thiyagarajan A, Platzbecker K, Ittermann T, Völzke H, Haug U. Estimating incidence and case fatality of thyroid storm in Germany between 2007 and 2017: A claims data analysis. Thyroid. 2022;32(11):1307-1315.
  https://doi.org/10.1089/thy.2022.0096
  https://repository.publisso.de/resource/frl%3A6435247
• Wentzell N, Haug U. Characterization of pregnancies among women with epilepsy using valproate before or during pregnancy - A longitudinal claims data analysis from Germany. Epilepsy Research. 2022;179:106838.
  https://doi.org/10.1016/j.eplepsyres.2021.106838
  https://repository.publisso.de/resource/frl:6431122
• Boakye D, Günther K, Niedermaier T, Haug U, Ahrens W, Nagrani R. Associations between comorbidities and advanced stage diagnosis of lung, breast, colorectal, and prostate cancer: A systematic review and meta-analysis. Cancer Epidemiology. 2021;75:102054.
  https://doi.org/10.1016/j.canep.2021.102054
  https://repository.publisso.de/resource/frl%3A6430337
• Boakye D, Nagrani R, Ahrens W, Haug U, Günther K. The association of comorbidities with administration of adjuvant chemotherapy in stage III colon cancer patients: A systematic review and meta-analysis. Therapeutic Advances in Medical Oncology. 2021;13:1758835920986520.
  https://doi.org/10.1177/1758835920986520
• Börnhorst C, Reinders T, Rathmann W, Bongaerts B, Haug U, Didelez V, Kollhorst B. Avoiding time-related biases: A feasibility study on antidiabetic drugs and pancreatic cancer applying the parametric g-formula to a large German healthcare database. Clinical Epidemiology. 2021;(13):1027-1038.
  https://doi.org/10.2147/CLEP.S328342
• Heinig M, Braitmaier M, Haug U. Prescribing of menopausal hormone therapy in Germany: Current status and changes between 2004 and 2016. Pharmacoepidemiology and Drug Safety. 2021;30(4):462-471.
  https://doi.org/10.1002/pds.5186
• Heinig M, Schwarz S, Haug U. Self-selection for mammography screening according to use of hormone replacement therapy: A systematic literature review. Cancer Epidemiology. 2021;71(Part A):101812.
  https://doi.org/10.1016/j.canep.2020.101812
  https://repository.publisso.de/resource/frl:6425860
• Komen J, Pottegård A, Mantel-Teeuwisse A, Forslund T, Hjemdahl P, Wettermark B, Hellfritzsch M, Hallas J, Olesen M, Bennie M, Mueller T, Voss A, Schink T, Haug U, Kollhorst B, Karlstad Ø, Kjerpeseth LJ, Klungel O. Persistence and adherence to non-vitamin K antagonist oral anticoagulant treatment in patients with atrial fibrillation across five Western European countries. Europace. 2021;23(11):1722-1730.
  https://doi.org/10.1093/europace/euab091
• Marron M, Brackmann K, Kuhse P, Christianson L, Langner I, Haug U, Ahrens W. Vaccination and the risk of childhood cancer - A systematic review and meta-analysis. Frontiers in Oncology. 2021;10:610843.
  https://doi.org/10.3389/fonc.2020.610843
• Oppelt KA, Kuiper JG, Ingrasciotta Y, Ientile V, Herings R, Tari M, Trifirò G, Haug U. Characteristics and absolute survival of metastatic colorectal cancer patients treated with biologics: A real-world data analysis from three European countries. Frontiers in Oncology. 2021;11:630456.
  https://doi.org/10.3389/fonc.2021.630456
• Reinold J, Braitmaier M, Riedel O, Haug U. Anticholinergic burden: First comprehensive analysis using claims data shows large variation by age and sex. PLOS ONE. 2021;16(6):e0253336.
  https://doi.org/10.1371/journal.pone.0253336
• Schäfer W, Reinders T, Riedel O, Haug U. How often are antidepressants prescribed off-label among older adults in Germany? A claims data analysis. British Journal of Clinical Pharmacology. 2021;87(4):1778-1789.
  https://doi.org/10.1111/bcp.14564
• Schäfer W, Wentzell N, Schink T, Haug U. Characterization of pregnancies exposed to St. John's wort and their outcomes: A claims data analysis. Reproductive Toxicology. 2021;102:90-97.
  https://doi.org/10.1016/j.reprotox.2021.04.005
  https://repository.publisso.de/resource/frl%3A6428346
• Scholle O, Neubert A, Riedel O, Toni I, Haug U. Repeated use of prescription drugs in pediatrics: Comprehensive overview based on German claims data. Frontiers in Pharmacology. 2021;12:706682.
  https://doi.org/10.3389/fphar.2021.706682
• Schwarz S, Oppelt KA, Heinig M, Haug U. Potential of German claims data to characterize utilization of new cancer drugs: The example of crizotinib. Future Oncology. 2021;17(18):2305-2313.
  https://doi.org/10.2217/fon-2020-1052
  https://repository.publisso.de/resource/frl:6428548
• Schwarz S, Schäfer W, Horenkamp-Sonntag D, Liebentraut J, Haug U. Follow-up of 3 million persons undergoing colonoscopy in Germany: Utilization of repeat colonoscopies and polypectomies within 10 years. Clinical and Translational Gastroenterology. 2021;12(1):e00279.
  https://doi.org/10.14309/ctg.0000000000000279
• Zeeb H, Ahrens W, Haug U, Grabenhenrich L, Pigeot I. Epidemiologische Ansätze zur Klärung wichtiger Forschungsfragen zu COVID-19 - Eine Übersicht. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2021;64(9):1076-1083.
  https://doi.org/10.1007/s00103-021-03378-x
• Beyerle J, Holowatyj AN, Haffa M, Frei E, Gigic B, Schrotz-King P, Böhm J, Habermann N, Stiborova M, Scherer D, Koelsch T, Skender S, Becker N, Herpel E, Schneider M, Ulrich A, Schirmacher P, Chang-Claude J, Brenner H, Hoffmeister M, Haug U, Owen RW, Ulrich CM. Expression patterns of xenobiotic-metabolizing enzymes in tumor and adjacent normal mucosa tissues among patients with colorectal cancer: The ColoCare Study. Cancer Epidemiology, Biomarkers & Prevention. 2020;29(2):460-469.
  https://doi.org/10.1158/1055-9965.EPI-19-0449
• Haug U, Coupé VMH. The cumulative false-positive rate in colorectal cancer screening: A Markov analysis. European Journal of Gastroenterology and Hepatology. 2020;32(5):575-580.
  https://doi.org/10.1097/MEG.0000000000001669
• Krueger K, Jobski K, Voss A, Haug U. Different risk profiles of European patients using direct oral anticoagulants or vitamin K antagonists: A rapid review. Current Epidemiology Reports. 2020;7(4):290-299.
  https://doi.org/10.1007/s40471-020-00257-y
• Langner I, Riedel O, Czwikla J, Heinze F, Rothgang H, Zeeb H, Haug U. Linkage of routine data to other data sources in Germany: A practical example illustrating challenges and solutions. Das Gesundheitswesen. 2020;82(Suppl. 2):S117-S121.
  https://doi.org/10.1055/a-0999-5509
• Pisa F, Reinold J, Kollhorst B, Haug U, Schink T. Individual antidepressants and the risk of fractures in older adults: A new user active comparator study. Clinical Epidemiology. 2020;12:667-678.
  https://doi.org/10.2147/CLEP.S222888
• Schink T, Wentzell N, Dathe K, Onken M, Haug U. Estimating the beginning of pregnancy in German claims data: Development of an algorithm with a focus on the expected delivery date. Frontiers in Public Health. 2020;8:350.
  https://doi.org/10.3389/fpubh.2020.00350
• Scholle O, Kollhorst B, Haug U. Are prescribers not aware of cardiovascular contraindications for diclofenac? A claims data analysis. Journal of Internal Medicine. 2020;287(2):171-179.
  https://doi.org/10.1111/joim.12990
• Buskermolen M, Cenin DR, Helsingen LM, Guyatt G, Vandvik PO, Haug U, Bretthauer M, Lansdorp-Vogelaar I. Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: A microsimulation modelling study. The BMJ. 2019;367:l5383.
  https://doi.org/10.1136/bmj.l5383
• Langner I, Haug U, Scholle O, Lindemann C, Schröder C, Riedel O. Potential explanations for increasing methylphenidate use in children and adolescents with attention-deficit/hyperactivity disorder in Germany from 2004 to 2013. Journal of Clinical Psychopharmacology. 2019;39(1):39-45.
  https://doi.org/10.1097/JCP.0000000000000980
  https://repository.publisso.de/resource/frl%3A6423245
• Langner I, Ohlmeier C, Haug U, Hense H-W, Czwikla J, Zeeb H. Implementation of an algorithm for the identification of breast cancer deaths in German health insurance claims data: A validation study based on a record linkage with administrative mortality data. BMJ Open. 2019;9:e026834.
  https://doi.org/10.1136/bmjopen-2018-026834
• Langner I, Ohlmeier C, Zeeb H, Haug U, Riedel O. Individual mortality information in the German Pharmacoepidemiological Research Database (GePaRD): A validation study using a record linkage with a large cancer registry. BMJ Open. 2019;9:e028223.
  https://doi.org/10.1136/bmjopen-2018-028223
• Oppelt KA, Luttmann S, Kraywinkel K, Haug U. Incidence of advanced colorectal cancer in Germany: Comparing claims data and cancer registry data. BMC Medical Research Methodology. 2019;19:142.
  https://doi.org/10.1186/s12874-019-0784-y
• Overbeek J, Kuiper J, van der Heijden A, Labots M, Haug U, Herings R, Nijpels G. Sex- and site-specific differences in colorectal cancer risk among people with type 2 diabetes. International Journal of Colorectal Disease. 2019;34(2):269-276.
  https://doi.org/10.1007/s00384-018-3191-7
• Pisa F, Reinold J, Kollhorst B, Haug U, Schink T. Antidepressants and the risk of traumatic brain injury in the elderly: Differences between individual agents. Clinical Epidemiology. 2019;11:185-196.
  https://doi.org/10.2147/CLEP.S173667
• Bauer A, Riemann JF, Seufferlein T, Reinshagen M, Hollerbach S, Haug U, Unverzagt S, Boese S, Ritter-Herschbach M, Jahn P, Frese T, Harris M, Landenberger M. Invitation to screening colonoscopy in the population at familial risk for colorectal cancer: A cluster-randomized study aimed at increasing participation rates. Deutsches Ärzteblatt International. 2018;115(43):715-722.
  https://doi.org/10.3238/arztebl.2018.0715
• Czwikla J, Giersiepen K, Langner I, Enders D, Heinze F, Rothgang H, Haug U, Zeeb H, Hense H-W. A cohort study of mammography screening finds that comorbidity measures are insufficient for controlling selection bias. Journal of Clinical Epidemiology. 2018;104:1-7.
  https://doi.org/10.1016/j.jclinepi.2018.07.014
• Haug U. Aktueller Stand der Evidenz und Entwicklung der Darmkrebsfrüherkennung in Deutschland. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2018;61(12):1513-1516.
  https://doi.org/10.1007/s00103-018-2832-x
• Haug U, Langner I, Zeeb H. Evaluation von organisierten Programmen zur Krebsfrüherkennung: Allgemeine Aspekte und aktueller Stand in Deutschland. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2018;61(12):1500-1504.
  https://doi.org/10.1007/s00103-018-2831-y
• Haug U, Riedel O, Cholmakow-Bodechtel C, Olsson L. First-degree relatives of cancer patients: A target group for primary prevention? A cross-sectional study. British Journal of Cancer. 2018;118(9):1255-1261.
  https://doi.org/10.1038/s41416-018-0057-2
• Oppelt KA, Haug U. Schmerztherapie bei Darmkrebspatienten - Längsschnittanalysen auf Versichertendaten basierend. Der Onkologe. 2018;24(11):848-860.
  https://doi.org/10.1007/s00761-018-0468-y
  https://repository.publisso.de/resource/frl%3A6417337
• Plath J, Siebenhofer A, Haug U, Koné I, Hechtner M, Blumenstein I, Schulz-Rothe S, Gerlach FM, Guethlin C. Utilization of colonoscopy and colonoscopic findings among individuals aged 40-54 years with a positive family history of colorectal cancer: A cross-sectional study in general practice. European Journal of Cancer Prevention. 2018;27(6):539-545.
  https://doi.org/10.1097/CEJ.0000000000000399
• Rutter MD, Beintaris I, Valori R, Chiu HM, Corley D, Dekker E, Forsberg A, Freixas MC, Gore-Booth J, Haug U, Kaminski MF, Matsuda T, Meijer GA, Morris E, Plumb A, Rabeneck L, Robertson D, Schoen R, Singh H, Tinmouth J, Young G, Sanduleanu S. World Endoscopy Organization consensus statements on post-colonoscopy and post-imaging colorectal cancer. Gastroenterology. 2018;155(3):909-925.e3.
  https://doi.org/10.1053/j.gastro.2018.05.038
  https://eprints.whiterose.ac.uk/131233/
• Wentzell N, Haug U, Schink T, Engel S, Liebentraut J, Linder R, Onken M, Schaefer C, Dathe K. Valproatverordnungen bei Mädchen und Frauen im gebärfähigen Alter in Deutschland: Untersuchung zeitlicher Trends basierend auf Versichertendaten. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2018;61(8):1022-1029.
  https://doi.org/10.1007/s00103-018-2768-1
• Wentzell N, Schink T, Haug U, Ulrich S, Niemeyer M, Mikolajczyk R. Optimizing an algorithm for the identification and classification of pregnancy outcomes in German claims data. Pharmacoepidemiology and Drug Safety. 2018;27(9):1005-1010.
  https://doi.org/10.1002/pds.4588
  https://repository.publisso.de/resource/frl%3A6417552
• Haug U, Grobbee EJ, Lansdorp-Vogelaar I, Spaander MCW, Kuipers EJ. Immunochemical faecal occult blood testing to screen for colorectal cancer: Can the screening interval be extended. Gut. 2017;66(7):1262-1267.
  https://doi.org/10.1136/gutjnl-2015-310102
• Zia Shams A, Haug U. Strategies for prevention of gastrointestinal cancers in developing countries: A systematic review. Journal of Global Health. 2017;7(2):020405.
  https://doi.org/10.7189/jogh.07.020405
• Fiederling J, Zia Shams A, Haug U. Validity of self-reported family history of cancer: A systematic literature review on selected cancers. International Journal of Cancer. 2016;139(7):1449-1460.
  https://doi.org/10.1002/ijc.30203
• Haug U, Becker N. Immunologische Stuhlbluttests zur Darmkrebsfrüherkennung: Schnelltests sind keine vertretbare Option für ein qualitätsgesichertes Programm. Deutsche Medizinische Wochenschrift. 2016;141(10):729-731.
  https://doi.org/10.1055/s-0042-104048
• Young GP, Senore C, Mandel JS, Allison JE, Atkin WS, Benamouzig R, Bossuyt P, De Silva M, Guittet L, Halloran SP, Haug U, Hoff G, Itzkowitz SH, Leja M, Levin B, Meijer GA, O'Morain CA, Parry S, Rabeneck L, Rozen P, Saito H, Schoen RE, Seaman HE, Steele RJC, Sung JJY, Winawer SJ. Recommendations for a step-wise comparative approach to the evaluation of new screening tests for colorectal cancer. Cancer. 2016;122(6):826-839.
  https://doi.org/10.1002/cncr.29865
• Hermann S, Friedrich S, Haug U, Rohrmann S, Becker N, Kaaks R. Association between socio-economic and demographic characteristics and utilization of colonoscopy in the EPIC-Heidelberg cohort. 2015.
  https://doi.org/10.1097/CEJ.0000000000000080
• Fiederling J, Ulrich C, Hemminki K, Haug U. Consideration of family history of cancer in medical routine: A survey in the primary care setting in Germany. 2014.
  https://doi.org/10.1097/CEJ.0b013e328364743d
• Haug U, Engel S, Verheyen F, Linder R. Estimating colorectal cancer treatment costs: A pragmatic approach exemplified by health insurance data from Germany. 2014.
  https://doi.org/10.1371/journal.pone.0088407
• Haug U, Knudsen AB, Lansdorp-Vogelaar I, Kuntz KM. Development of new non-invasive tests for colorectal cancer screening: The relevance of information on adenoma detection. 2014.
  https://doi.org/10.1002/ijc.29343
• Haug U, Rösch T, Hoffmeister M, Katalinic A, Brenner H, Becker N. Einführung eines organisierten Darmkrebs-Screenings in Deutschland: Chancen und Herausforderungen. 2014.
  https://doi.org/10.1055/s-0034-1377027
• Ordonez-Mena JM, Schöttker B, Haug U, Muller H, Kohrle J, Schomburg L, Holleczek B, Brenner H. Serum 25-hydroxyvitamin D and cancer risk in older adults: Results from a large German prospective cohort study. 2013.
  https://doi.org/10.1158/1055-9965.EPI-12-1332
• Perna L, Butterbach K, Haug U, Schöttker B, Müller H, Arndt V, Holleczek B, Burwinkel B, Brenner H. Vitamin D receptor genotype rs731236 (Taq1) and breast cancer prognosis. 2013.
  https://doi.org/10.1158/1055-9965.EPI-12-0970-T
• Perna L, Felix JF, Breitling LP, Haug U, Raum E, Burwinkel B, Schöttker B, Brenner H. Genetic variations in the vitamin D binding protein and season-specific levels of vitamin D among older adults. 2013.
  https://doi.org/10.1097/EDE.0b013e318276c4b0
• Perna L, Hoffmeister M, Schöttker B, Arndt V, Haug U, Holleczek B, Burwinkel B, Ordonez-Mena JM, Brenner H. Vitamin D receptor polymorphism and colorectal cancer-specific and all-cause mortality. 2013.
  https://doi.org/10.1016/j.canep.2013.09.007
• Schöttker B, Haug U, Schomburg L, Köhrle J, Perna L, Müller H, Holleczek B, Brenner H. Strong associations of 25-hydroxyvitamin D concentrations with all-cause, cardiovascular, cancer, and respiratory disease mortality in a large cohort study. 2013.
  https://doi.org/10.3945/ajcn.112.047712
• Bünger S, Haug U, Kelly M, Posorski N, Klempt-Giessing K, Cartwright A, Fitzgerald SP, Toner V, McAleer D, Gemoll T, Laubert T, Büning J, Fellermann K, Bruch H-P, Roblick UJ, Brenner H, von Eggeling F, Habermann JK. A novel multiplex-protein array for serum diagnostics of colon cancer: A case-control study. 2012.
  https://doi.org/10.1186/1471-2407-12-393
• Haug U, Knudsen AB, Kuntz KM. How should individuals with a false-positive fecal occult blood test for colorectal cancer be managed? A decision analysis. 2012.
  https://doi.org/10.1002/ijc.27463
• Haug U, Poole EM, Xiao L, Curtin K, Duggan D, Makar KW, Peters U, Kulmacz RJ, Potter JD, Koepl L, Caan BJ, Slattery ML, Ulrich CM. Glutathione peroxidase tagSNPs: Associations with rectal cancer but not with colon cancer. 2012.
  https://doi.org/10.1002/gcc.21946
• Perna L, Haug U, Schöttker B, Müller H, Raum E, Jansen E, Brenner H. Public health implications of standardized 25-hydroxyvitamin D levels: A decrease in the prevalence of vitamin D deficiency among older women in Germany. 2012.
  https://doi.org/10.1016/j.ypmed.2012.06.010
• Schöttker B, Jansen EH, Haug U, Schomburg L, Köhrle J, Brenner H. Standardization of misleading immunoassay based 25-hydroxyvitamin D levels with liquid chromatography tandem-mass spectrometry in a large cohort study. 2012.
  https://doi.org/10.1371/journal.pone.0048774
• Stock C, Pulte D, Haug U, Brenner H. Subsite-specific colorectal cancer risk in the colorectal endoscopy era. 2012.
  https://doi.org/10.1016/j.gie.2011.10.025
• Tao S, Haug U, Kuhn K, Brenner H. Comparison and combination of blood-based inflammatory markers with faecal occult blood tests for non-invasive colorectal cancer screening. 2012.
  https://doi.org/10.1038/bjc.2012.104
• Bünger S, Haug U, Kelly FM, Klempt-Giessing K, Cartwright A, Posorski N, Dibbelt L, Fitzgerald SP, Bruch H-P, Roblick UJ, von Eggeling F, Brenner H, Habermann JK, on behalf of the BMBF consortium "Colorectal Cancer Screening Chip". Toward standardized high-throughput serum diagnostics: Multiplex-protein array identifies IL-8 and VEGF as serum markers for colon cancer. 2011.
  https://doi.org/10.1177/1087057111414894
• Haug U, Brenner H, Knudsen AB, Kuntz KM. Is fecal occult blood testing more sensitive for left- than for right-sided colorectal neoplasia? A systematic review. 2011.
  https://doi.org/10.1586/erm.11.41
• Haug U, Kuntz KM, Knudsen AB, Hundt S, Brenner H. Sensitivity of fecal occult blood testing for detecting left- vs right-sided advanced neoplasia. 2011.
  https://doi.org/10.1038/bjc.2011.160
• Stock C, Knudsen AB, Lansdorp-Vogelaar I, Haug U, Brenner H. Colorectal cancer mortality prevented by use and attributable to nonuse of colonoscopy. 2011.
  https://doi.org/10.1016/j.gie.2010.12.005
• Tao S, Hundt S, Haug U, Brenner H. Sensitivity of blood-based tests for colorectal cancer detection: Impact of overrepresentation of advanced stage disease. 2011.
  https://doi.org/10.1038/ajg.2010.393
• Yin L, Grandi N, Raum E, Haug U, Arndt V, Brenner H. Meta-analysis: Circulating vitamin D and ovarian cancer risk. 2011.
  https://doi.org/10.1016/j.ygyno.2011.01.023
• Yin L, Grandi N, Raum E, Haug U, Arndt V, Brenner H. Meta-analysis: Serum vitamin D and colorectal adenoma risk. 2011.
  https://doi.org/10.1016/j.ypmed.2011.05.013
• Brenner H, Haug U, Arndt V, Stegmaier C, Altenhofen L, Hoffmeister M. Low risk of colorectal cancer and advanced adenomas more than 10 years after negative colonoscopy. 2010.
  https://doi.org/10.1053/j.gastro.2009.10.054
• Brenner H, Haug U, Hundt S. Inter-test agreement and quantitative cross-validation of immunochromatographical fecal occult blood tests. 2010.
  https://doi.org/10.1002/ijc.25154
• Brenner H, Haug U, Hundt S. Sex differences in performance of fecal occult blood testing. 2010.
  https://doi.org/10.1038/ajg.2010.301
• Brenner H, Hoffmeister M, Arndt V, Stegmaier C, Altenhofen L, Haug U. Protection from right- and left-sided colorectal neoplasms after colonoscopy: Population-based study. 2010.
  https://doi.org/ 10.1093/jnci/djp436
• Brenner H, Tao S, Haug U. Low dose aspirin use and performance of immunochemical fecal occult blood tests. 2010.
  https://doi.org/10.1001/jama.2010.1773
• Haug U, Hundt S, Brenner H. Quantitative immunochemical fecal occult blood testing for colorectal adenoma detection: Evaluation in the target population of screening and comparison with qualitative tests. 2010.
  https://doi.org/10.1038/ajg.2009.668
• Hoffmeister M, Schmitz S, Karmrodt E, Stegmaier C, Haug U, Arndt V, Brenner H. Male sex and smoking have a larger impact on the prevalence of colorectal neoplasia than family history of colorectal cancer. 2010.
  https://doi.org/10.1016/j.cgh.2010.07.004
• Sieverding M, Matterne U, Ciccarello L, Haug U. Colonoscopy use in a country with a long-standing colorectal cancer screening programme: Evidence from a large German survey. 2010.
  https://doi.org/10.1055/s-0029-1245611
• Stock C, Haug U, Brenner H. Population-based prevalence estimates of history of colonoscopy or sigmoidoscopy: review and analysis of recent trends. 2010.
  https://doi.org/10.1016/j.gie.2009.06.018
• Yin L, Grandi N, Raum E, Haug U, Arndt V, Brenner H. Meta-analysis: Serum vitamin D and breast cancer risk. 2010.
  https://doi.org/10.1016/j.ejca.2010.03.037
• Brenner H, Hoffmeister M, Brenner G, Altenhofen L, Haug U. Expected reduction of colorectal cancer incidence within 8 years after introduction of the German screening colonoscopy programme: Estimates based on 1,875,708 screening colonoscopies. 2009.
  https://doi.org/10.1016/j.ejca.2009.02.017
• Hundt S, Haug U, Brenner H. Comparative evaluation of immunochemical fecal occult blood tests for colorectal adenoma detection. 2009.
  https://doi.org/10.7326/0003-4819-150-3-200902030-00005
• Yin L, Grandi N, Raum E, Haug U, Arndt V, Brenner H. Meta-analysis: Longitudinal studies of serum vitamin D and colorectal cancer risk. 2009.
  https://doi.org/10.1111/j.1365-2036.2009.04022.x
• Yin L, Raum E, Haug U, Arndt V, Brenner H. Meta-analysis of longitudinal studies: Serum vitamin D and prostate cancer risk. 2009.
  https://doi.org/10.1016/j.canep.2009.10.014
• Brenner H, Hoffmeister M, Haug U. Family history and age at initiation of colorectal cancer screening. 2008.
  https://doi.org/10.1111/j.1572-0241.2008.01978.x
• Brenner H, Hooffmeister M, Haug U. Should colorectal cancer screening start at the same age in European countries? Contributions from descriptive epidemiology. 2008.
  https://doi.org/10.1038/sj.bjc.6604488
• Haug U, Hundt S, Brenner H. Sensitivity and specificity of faecal tumour M2 pyruvate kinase for detection of colorectal adenomas in a large screening study. 2008.
  https://doi.org/10.1038/sj.bjc.6604427
• Haug U, Wente M, Seiler CM, Jesnowski R, Brenner H. Stool testing for the early detection of pancreatic cancer: Rationale and current evidence. 2008.
  https://doi.org/10.1586/14737159.8.6.753
• Müller H, Haug U, Rothenbacher D, Stegmaier C, Brenner H. Evaluation of serum and urinary myeloid related protein-14 as a marker for early detection of prostate cancer. 2008.
  https://doi.org/10.1016/j.juro.2008.06.025
• Brenner H, Hoffmeister M, Arndt V, Haug U. Gender differences in colorectal cancer: Implications for age at initiation of screening. 2007.
  https://doi.org/10.1038/sj.bjc.6603628
• Brenner H, Hoffmeister M, Stegmaier C, Brenner G, Altenhofen L, Haug U. Risk of progression of advanced adenomas to colorectal cancer by age and sex: Estimates based on 840,149 screening colonoscopies. 2007.
  https://doi.org/10.1136/gut.2007.122739
• Haug U, Hillebrand T, Bendzko P, Low M, Rothenbacher D, Stegmaier C, Brenner H. Mutant-enriched PCR and allele-specific hybridization reaction to detect K-ras mutations in stool DNA: High prevalence in a large sample of older adults. 2007.
  https://doi.org/10.1373/clinchem.2006.078188
• Haug U, Rothenbacher D, Wente MN, Seiler CM, Stegmaier C, Brenner H. Tumour M2-PK as a stool marker for colorectal cancer: Comparative analysis in a large sample of unselected older adults vs colorectal cancer patients. 2007.
  https://doi.org/10.1038/sj.bjc.6603712
• Hundt S, Haug U, Brenner H. Blood markers for early detection of colorectal cancer: A systematic review. 2007.
  https://doi.org/10.1158/1055-9965.EPI-06-0994
• Haug U, Wente MN, Seiler CM, Rothenbacher D, Buchler MW, Brenner H. Tumor-M2-PK as a stool marker for colorectal cancer: Stability at room temperature and implications for application in the screening setting. 2006.
  https://doi.org/10.1373/clinchem.2005.062752
• Haug U, Brenner H. New stool tests for colorectal cancer screening: A systematic review focusing on performance characteristics and practicalness. 2005.
  https://doi.org/10.1002/ijc.21016
• Haug U, Brenner H. A simulation model for colorectal cancer screening: Potential of stool tests with various performance characteristics compared to screening colonoscopy. 2005.
  https://doi.org/10.1158/1055-9965.EPI-04-0411

• Commentaries

• Haug U, Senore C, Corley D. Promises and potential pitfalls of shared decision-making in cancer screening. 2020.
  https://doi.org/10.1053/j.gastro.2019.11.293
• Senore C, Haug U. Faecal immunochemical tests have the potential for correctly ruling out colorectal cancer in symptomatic patients. 2018.
  https://doi.org/10.1136/bmjebm-2018-110901

• Editorials

• Haug U, Pigeot I. Krebsfrüherkennung: Ja oder Nein? Facetten einer komplexen Antwort. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2018;61(12):1481-1483.
  https://doi.org/10.1007/s00103-018-2844-6
• Haug U. Flexible sigmoidoscopy screening for colorectal cancer. The BMJ. 2017;356:j75.
  https://doi.org/10.1136/bmj.j75

• Stellungnahmen

• Deutsche Gesellschaft für Epidemiologie (DGEpi). Stellungnahme zum Beschlussentwurf des G-BA: Richtlinie für organisierte Krebsfrüherkennungsprogramme und Änderung der Krebsfrüherkennungs-Richtlinie. 2018.

• Herausgeberschaften

• Stand der Krebsfrüherkennung in Deutschland. 2018.

• Buchbeiträge

• Haug U. Screening des kolorektalen Karzinoms. Berlin, Heidelberg. 2020.
  https://doi.org/10.1007/978-3-662-46764-0_76-1

• Weitere Publikationen

• Vision Zero Präventionsaward 2020
  Netzwerk gegen Krebs (2020)
  Besondere Verdienste zum Thema Prävention und Früherkennung von Darmkrebs
• Mitglied von / Member of
  AcademiaNet – Expert Database of Outstanding Women in Science (2017)
• Darmkrebs-Präventionspreis 2016 / Colorectal Cancer Prevention Award 2016
  Deutsche Krebsgesellschaft, Stiftung LebensBlicke und Deutsche Krebsstiftung (2016)
  Darmkrebsvorsorge und -früherkennung
• Reisestipendium (travel grant) “Best submitted abstracts” / Oral Free Paper Prize
  United European Gastroenterology Week (2014)
• Felix-Burda-Award for Medical Prevention
  Felix Burda Stiftung (2009)
  Förderung der Darmkrebsprävention und -früherkennung in Deutschland
• Young Scientist Award (1st prize) of the German Epidemiological Association
  Deutsche Gesellschaft für Epidemiologie (2005)
• Promotionsstipendium 2002-2005 / PhD scholarship
  Deutsche Forschungsgemeinschaft (2002)

• Master-Studiengang Epidemiologie der Universität Bremen
• Bachelor-Studiengang Public Health/Pflegewissenschaft der Universität Bremen